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Injecting - Nubain (Nalbuphine HCL)

Discussion in 'Opiates & Opioids' started by Jessica_R, Apr 12, 2009.

  1. Jessica_R

    Jessica_R Newbie

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    SWIM weighs 95 lbs (Give or take). SWIM recently found a connection with a hospital worker. SWIM can get Nubain and phenergan (promethazine) vials for $xxx for BOTH of them and the new sterile needle. The needle is the big one like the one doctors give you when you get a shot in the bum.
    SWIM takes around 10 of the hydrocodone the 10/325 a day. SWIM cut down from 14 of the 7.5mg ones a day. SWIM wanted to know if there were any recreational values from the Nubain alone because the hospital worker said to mix both the vials in the needle and inject them into SWIM's butt (Upper right part), but SWIM hates the way promethazine makes SWIM feel.
    So back to SWIM's original question, any recreation value for the Nubain alone? and if so what would be the best way to use it?
     
    Last edited by a moderator: Apr 13, 2009
  2. trannyboy

    trannyboy Newbie

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    I wouldn't recommend injecting the promethazine. If you look in this forum there is a post recently about promethazine and at the very least it was agreed the I.V. injection was not worth the extreme dangers. I know that promethazine is injected IM and SC for other purposes but I would be hesitant to inject it unless your doctor has prescribed continuing injection (IM or SC) in the past for legitimate medical purposes. There are a couple of people on this forum who know a lot more then me about promethazine, hopefully they will have some suggestions.

    In terms of the nubain here are my concerns but bear in mind that I haven't personally used it or had the opertunity to use it in my professional life. Since SWIyou have been taking hydrocodone regularly SWIyou are likely addicted and hydrocodone is a pure agonist. It is known that taking a mixed agonist/ antagonist like nubain can cause as acute withdrawl syndrome in people who are addicted to a pure agonist like hydrocodone. My concern would be that SWIyou could cause a serious withdrawl very quickly that could be physically dangerous. I am hoping others will have more information but I wouldn't recommend taking that drug because of the above concerns.

    Despite this nubain AKA Nalbuphine may have some recreation usage. I would be inclinded to wait and see what others have to say before SWIyou proceed. Best of luck no matter what SWIyou do.

    trannyboy
     
  3. Jessica_R

    Jessica_R Newbie

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    This past week SWIM hasn't been able to get hydrocodone. The most she can get is about 5 of the 5/500. So the most SWIM has taken a day is 15mg. Idk if that helps any.
     
  4. trannyboy

    trannyboy Newbie

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    How long has SWIyou being taking the hydrocodone (both in general and daily use) and have SWIyou had symptoms of withdrawl when SWIyou couldn't take it? If SWIyou don't have any physical addiction SWIyou should be alright but if SWIyou have had any physical addiction SWIyou will probably have problems. The severity should be based on the level of addiction.

    trannyboy
     
  5. Jessica_R

    Jessica_R Newbie

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    I'd say a year give or take. There have been periods where SWIM has quit for a little less than a month. like SWIM said before this past week shes only been taking 15-25 mgs a day. SWIM doesn't take the promethazine but knows a lot of people who do and since it comes free with it might as well sale it. And as for withdrawals SWIM will just wake up in cold sweats. That's pretty much it besides craving it a little bit.
     
    Last edited by a moderator: Apr 13, 2009
  6. ganjahero420

    ganjahero420

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    ^ no prices!! read the rules your pricing and incriminating yourself. if your gonna be here please respect the rules. as the OP said dont IV promethazine and dont IV ANYTHING unless swiy seriously knows what they are doing. as for nubaine i have no experience with it. the promethazine has no value on its own it will jsut potentiate the nubaine.
     
  7. Jessica_R

    Jessica_R Newbie

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    :confused:I'd say a year give or take. There have been periods where SWIM has quit for a little less than a month. like SWIM said before this past week shes only been taking 15-25 mgs a day. SWIM doesn't take the promethazine but knows a lot of people who do and since it comes free with it might as well sale it. And as for withdrawals SWIM will just wake up in cold sweats. That's pretty much it besides craving it a little bit.
     
  8. pinksox

    pinksox Palladium Member

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    Nubain is both an opioid agonist AND antagonist. It will throw an opiate-dependent person into withdrawals..although it's great for opiate-naive ppl. SWIM never gives Nubain to any patient on long-term opioids. IF one is opiate-dependent DO NOT USE NUBAIN!!!

    The IV dose of Phenergan is 6.25-12.5mg pushed slow over 1-2 minutes. Start low as one can't take back too much but can always add more. SWIM also adds normal saline to the rest of the syringe as Phenergan is fairly hard (burns) on the inside of veins. Always better to dilute as much as possible.

    Honestly, Phenergan(promethazine) is quite easy to get at an MD appt just for the asking. Say SWIY has been getting nausea with headaches...or, if one is prescribed them, SWIY has been getting nauseous from the opiates. It's not a controlled substance so docs pretty much give it out for the asking. Just be such to keep some Benedryl(diphenhydramine) in the house for the rare event of a dystonic reaction to the Phenergan. It's not worth screwing around with veins if one doesnt have to. And it should NEVER be done with the gauge of needle that's used to draw up from vials. One will wreck their veins damn fast that way.
     
    Last edited: Apr 13, 2009
  9. trannyboy

    trannyboy Newbie

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    Thanks Pinksox, I thought that was the case with the nubain.

    Yeah I am going to have to say don't take the nubain SWIjessica. You might be alright given the mild withdrawl but more likely then not it will cause you problems you don't want. As for IVing I know SWIyou said it was to be given IM in the butt but;) from personal experience it isn't worth it to give yourself a shot in the butt. Twisting your back like that will hurt most people's back. If SWIyou are going to give it IM then use your thigh. That muscle is large enough to take a fairly large injection though on you I would say no more then 3ml. Since I don't recommend selling/ giving away your medication I would say either try and get your money back or toss it. Take cae and play safe.

    trannyboy
     
  10. LinusMundane

    LinusMundane Silver Member

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    Wait, ten 10's a day is 100mg of oxy 14 7.5's is 105 mg's... You cut down 5 mg's lol SWIM realizes SWIY is talking about the APAP but it was still kinda funny.

    On the IV note, please find another way to take SWIY's stuff. IVing causes so many other problems and its just not worth it.

    LinusMundane added 1 Minutes and 14 Seconds later...

    obviously, SWIY meant Hydro above.

    LinusMundane added 0 Minutes and 46 Seconds later...

    arrgh lol SWIM meant SWIM instead of SWIY!!!
     
    Last edited: Apr 13, 2009
  11. Jessica_R

    Jessica_R Newbie

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    Aight so I guess SWIM just stay away from the Nubain?
     
  12. pinksox

    pinksox Palladium Member

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    SWIM wouldn't...but SWIM is opiate-dependent. Nubain would make SWIM, or any other opiate-dependent person, feel like complete shit.

    As far as the Phenergan(promethazine) goes...it's great for potentiating opiates, but it's soooo easily obtained in pill form that going the IV route really, really isn't worth it. The stuff is pretty caustic to veins and SWIY would definitely have to go obtain some proper IV injection needles as the ones used to draw up from vials are far too big for repeated IV use.

    Phenergan is so easily obtained if one has a decent relationship with their PCP they may even be willing to call it in to the pharmacy over the phone without even seeing SWIY. Puking with tension headaches or nausea from prescribed opiates are two common reasons it's prescribed. If not, it can easily be gotten from a quick office visit for the same reasons.

    Honestly, it's one of those meds SWIM believes should be OTC much like Zantac is. And, it is, in fact, OTC in many countrys other than the US.
     
    Last edited: Apr 14, 2009
  13. trannyboy

    trannyboy Newbie

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    Yeah the odds are the nubain will cause SWIjessica problems, so taking it is a bad idea. So the answer is don't take it. I know for SWIM it would be absolutely a horrible idea and possibly dangerous as rapid detox can cause serious health issues. I have to wonder why whoever supplied it to you would do it. Odds are they are a medical professional and likely are aware of your addiction. Perhaps they don't like you? I would be careful with anything else they recommend/ provide/ sell because they either want you to suffer or aren't that smart. Either one isn't a good thing in a supplier.

    There is no reason to IV promethazine and a lot of reasons not to. If you really must take it by needle then do it subcutaneous or IM. You can also use the liquid rectally and orally I believe. You could save it for a time when you have other opiates.

    Linus- I noticed that as well, kinda strange but to each there own. At least SWIjessica isn't using as much acetaminophen though and any decrease in dosage has to be a good thing.

    trannyboy
     
    Last edited: Apr 14, 2009
  14. Seantwoofsix

    Seantwoofsix Silver Member

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    Hello.
    I realize this post is old but I wanted to reply so that anyone who reads this in the future will have access to this knowledge. I hope you decided to take the (good) advice of many of these posters and not try injecting the Nubain. Nubain is a mixed agonist/antagonist, which is not to be confused with a partial agonist, like Subutex/Suboxone. You are clearly opiate tolerant (100 mgs of hydrocodone daily for an extended period of time) and taking Nubain would unquestionably throw you into severe withdrawals (essentially as severe of withdrawals as your body is capable of producing). This is because of the nature of the drug itself. As simply as I can put it: Nubain is a full and strong antagonist of the Mu-opiate receptor (the receptor that is responsible for inducing euphoria and sedation (as well as other effects), and the one that common opiates like morphine are agonists of. In addition, Nubain is a strong agonist of the Kappa-opiate receptor: it is responsible for (among other things) the disphoria that opiates such as morphine also produce, the notable difference is that morphine is a relatively weak agonist of the K-receptor compared to Nubain. To make this point as simple as possible: Nubain switches off the "good" opiate receptor and switches on the "bad one. The most notable effect that both pure agonists (like morphine) and Nubain share is analgesia (pain blocking), although it is a different type/level of analgesia. I think going into the differences in the pharmaco-dynamics of analgesia in both drugs is well beyond the scope of what I am trying to say here, but anyone seriously interested in this topic should look it up. Nubain is abused however, by those who are strictly looking for a strong pain-killer and who are not opiate tolerant (such as body-builders). This is very likely the reason that Nubain is not a scheduled drug (at least in the USA). In addition, I can offer some personal experience to this question: A"friend of mine" who was taking 8mgs of Subutex daily once ran out of medication one week early and acquired a 20ml vial of Nubain. Foolishly, he tried taking the Nubain (10mgs by intravenous administration) before refreshing his knowledge of the pharmacology of this drug. Needless to say, it was one of the worst decisions he ever made. It was, without a doubt, the worst opiate withdrawals he had ever experienced. Fortunately, these severe withdrawals did not last long (about two hours, max), but he would definitely and strongly recommend against any opiate tolerant person using Nubain. On a positive note, my friend was rudely reminded that he was not all-knowing when it came to pharmacology, and learned never again to take a pharmaceutical recreationally before he has a good understanding of its theoretical effects.

    Seantwoofsix added 6 Minutes and 56 Seconds later...

    You are absolutely right in everything you have said here. This is very good advice. "Rapid Detox" is a perfect phrase to sum up what would happen if an opiate tolerant person were to use nubain.
     
    Last edited: Mar 8, 2010
  15. Rascal9886

    Rascal9886 Newbie

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    Ok, take is from someone who just made this mistake. I'm a little older retired from the service, and after 4 tours, and then retirement. decided to pick up some old habbits. As drugs of any kind are not tolerated in the Military. So, due to pain from injuries inccured in the line of duty and a diagnosis of PTSD, I was in heaven. i'm not saying I dont suffer from these things I am just saying I used them to my advantage. But to stay on point. I take about 300mg of Oxycontin a day, I live in a country where I can just get it over the counter. However one day I heard of this Nubain, which already came in a vial and so I wouldn't have to go through the hassle of... yada yada yada.... so stupidly I filled up a nice big 1ml/10mg shot, and BANG, lets just say I didnt even make it to the toilet. I am not a doctor and I no nothing about pharmacology. but through trial and error. I know now don't take these together.
     
  16. Rascal9886

    Rascal9886 Newbie

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    also, AFOAF, was wondering if going back on Pain Killers like Oxy ect ect.... will have the same effect?
     
  17. stayupandplay

    stayupandplay Silver Member

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    The rapid detox for sure....but Swim used nubain for a time....he enjoyed it...nubain flows nicely through a 25gauge needle(insulin). Swim also muscled it in his delt, but your bum is fine. At the time,Swim didn't have an opiate dependence. He was alternating norcos(hydrocodone 10/325) and Nubain every other day. Not very exciting but that was the routine.
     
  18. Rascal9886

    Rascal9886 Newbie

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    I think I might not of been clear with what I was trying to learn,

    If this FOAF now were to take and Oxy, would there be some kind of harsh withdrawal from the Nubian
     
  19. stayupandplay

    stayupandplay Silver Member

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    I would have to brush up on my terminology...but I believe nubain is an opiate agonist. If swim is dependent/addicted to the oxycodone, then taking nubain before the opiates are out of your system would send swim into wd's. One should wait until one begins to feel wd symptoms before hitting the nubain.
    This is what folks do before suboxone is administered...that, or folks are given subutex(sp?) and then suboxone. The subutex(sp?) is bupenephrine without the nalaxone(sp?)
     
  20. Rascal9886

    Rascal9886 Newbie

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    Exactly my friends pet was on 300mg of Oxy a day, my pets friend lives in a land where slipping a Pharmacist a few extra bucks under the table can get him anything listed in the MIMS (aka known to man) so my friends little pet heard of this Nubian, scurried to the local pharmacy and got 2, 1ml vials, the little pet was so excited he might have found something he didnt have to crush up ...yadayada... So after a 10 mg shot, detox from the 300mg of oxy a day was so fast the poor little critter didnt even make it to the bath room, as the poor little guy was sitting on the can, sweating and shaking, hopeing not to pull an Elvis Presley, but after a few hours the poor little thing was able to make it to bed
    The question is if my friends little pet now takes Oxy, will it interact with the Nubian causing the same result?