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Effects - Phenibut...holy shit this stuff actually works!!

Discussion in 'Nootropics' started by sturdychinfilms, Apr 1, 2010.

  1. sturdychinfilms

    sturdychinfilms Mercury Member

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    I recently ordered a 100grams of phenibut powder. He wasn't really looking to get high (which he didn't) but just to eliminate anxiety. I was afraid that the phenibut would have no effect on him since he had been addicted to alprozalam(xanax) for a while and phenibut seemingly works on the GABA receptors like xanax does. He was wrong. After a dose around 2.5grams he felt great. Anxiety was gone, he was relaxed and comfortable and even had a slight uplifting buzz(not really too apparent though). Only thing that sucks is that it takes about 2 hours to kick in, and for I don't fully effect him until 3 hours in. BUT it does last for an incredibley long time. Also, this shit is fucking amazing for sex. SWIM can last almost indefinately on it. But it doesn't delay ejaculation like opiates do by just decreasing pleasure. SWIM still feels everything perfectly but feels he has ultimate control over his ejaculation. Also its pretty cheap too so thats awesome. I am going to experiment with higher dosages to see if he can get some sort of high out of it that people speak of. Also I would like to experiment mixing it with alcohol since the two apparently have synergistic properties. But in conclusion this shit works. If you are an avid user of drugs like GHB or benzos like SWIM then you probably wont get a high out of it. But it will decrease anxiety and make you a porn star in the bed.
     
  2. Slayerkorn

    Slayerkorn Newbie

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    It also works very well for SWIM as an anxyliotic. The only major downside is a "hangover" type feeling after using it. I had athrobbing headache and a blah feeling for about 2 weeks after taking pheni one weekend.

    Slayerkorn added 5 Minutes and 48 Seconds later...

    It also works very well for SWIM as an anxyliotic. The only major downside is a "hangover" type feeling after using it. I had athrobbing headache and a blah feeling for about 2 weeks after taking pheni one weekend.
     
    Last edited: May 8, 2010
  3. fiveleggedrat

    fiveleggedrat Palladium Member

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    Phenibut + Glutamine should really prove worthwhile. Glutamine -> GABA.

    Works with benzos, alcohol, and such. Why not phenibut?
     
  4. skunkjar

    skunkjar Newbie

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    I find phenibut to be extremely helpful for his anxiety. His wife gets the nasty "hangover" effect but SWIM just feels more mellow and less stressed the next day. It should be noted however tolerance builds pretty quick and those 2g doses quickly become 3-5g doses... Also it is said to be nearly as addictive as any other GABA drug so be cautious!
     
  5. zornthro

    zornthro Silver Member

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    I am taking this with aniracetam to see if aniracetam can decrease tolerance build up to the drug. He's been taking 750mg phenibut a day which is kind of a weak dose but does help his anxiety some. He takes it before going to work and will need something to treat his anxiety all summer otherwise he won't be able to continue working. Hopefully keeping the dose small will decrease the rate at which tolerance develops.

    There's another drug called baclofen that's very similar to phenibut. Baclofen however doesn't cause tolerance like phenibut does. Maybe phenibut overtime gets metabolised quicker by the liver or something. The two drugs target the same receptors so maybe baclofen is different in that your body doesn't start metabolising it faster over time. Phenibut is also a phenethylamine receptor antagonist so it's also possible that tolerance/withdrawal is caused by interfering with phenethylamine in the brain.
     
  6. Jasim

    Jasim Gold Member

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    Is there some basis for this? Source? What's the idea behind this? Where did You get this idea?
     
  7. zornthro

    zornthro Silver Member

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    I read it on a forum and told SWIM about it. Aniracetam antagonizes ampa receptors which is implicated in phinibut addiction (as well as benzo and opiod addiction). A few people have reported that aniracetam can bring back the original high on phenibut after it seems to have stopped working.

    NMDA receptors also modulate addiction for the same reason; these receptors become more active to compensate for the depressant effect of downers. GABAb receptors dont become desensitized so addiction to a GABAb receptor agonist would be entirely modulated through ampa and nmda receptors. As far as I know, at least.
     
  8. imyourlittlebare

    imyourlittlebare Palladium Member

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    SWIM wonders about that though. While there has been success using NMDA antagonist and NO synthesis inhibitors to reverse tolerance to opiates, SWIM never heard of similar success with benzos. In that regard, it seems to be specific GABA A subunits that induce tolerance through NMDA (particularly the NR2B receptor subtype) receptor.

    As far as phenibut goes, it seems like abstinence should do it. Theoretically, phenibut increases activity at GABA B receptor. Increased GABA B receptor activity leads to decreases in GABA, increased CA2+ channel activity, and decreased GABA A receptor activity. However it also leads to inhibition in certain brain areas. Does You think tolerance may be due to alterations in GABA A activity and extra synaptic GABA levels?
     
  9. mr t

    mr t Newbie

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    I remember reading in another forum that a very exp,' swimmer' will only do DOx compounds in combination with phenibut,claiming it adds alot to the euphoria factor:applause:
     
  10. JaWill88

    JaWill88 Newbie

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    yes phenibut is an incredible substance. used it for a long time but then just got baclofen which is almost the same, but works a little better, and tolerance never seems to build. but phenibut is amazing. I couldn't believe he didn't have anxiety after taking it, considering he has used many benzos (mainly clonazepam) for many years. and even after using benzos recently, that stuff does the trick. i give phenibut and A+ in my book. just cant use it for more than a few days, without a few day break. I like to use high doses like 10grams at a time. that really kills anxiety all day. and it will also potentiate some other gaba agonitsts, mainly gaba b agonists (ghb, baclofen, ect.)
     
  11. DiabolicScheme

    DiabolicScheme Titanium Member

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    Read new post below..
     
    Last edited: Nov 21, 2010
  12. NeuroChi

    NeuroChi is not his mind Platinum Member & Advisor

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    It is a strange blend of alcohol and a weakly anxiolytic benzo like lorazepam. Mild co-ordination impairment at 3 grams, with some relaxing anxiolytic effects on the mind and comfortable body buzz. Somewhat fuzzy headspace and potent effects on vision. Hardly something someone could ever safely drive under the influence of.
     
  13. imyourlittlebare

    imyourlittlebare Palladium Member

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    Its ridiculous to me that phenibut is considered a nootropic. It impairs short-term memory tasks in animals, the memory impairments are reversed through the use of scopalamine, and GABA B antagonists enhance learning/memory.

    SWIM wonders how this myth got started? Perhaps helped with performance anxiety on certain tests and particular ppl scored better? any You know?
     
  14. NeuroChi

    NeuroChi is not his mind Platinum Member & Advisor

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    I understand it help with sleep, which can be viewed in itself as a nootropic (or counter-nootropic) since some of them provide stimulation and phenibut could be used to counter this.

    Some data exists on phenibut as a nootropic in the classical sense though; it is used in Russia in place of Ritalin for those with ADHD, and has been compared to piracetam in effects.

    Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug

    Some of the studies quoted in the following passage are somewhat relevant, though it seems to jump to the conclusion that it is a nootropic because it enhances performance on a passive avoidance test. Personally I'm not convinced that will mean if I take it I will perform better on memory tests or cognitive ability, but hey, to each their own I suppose.

    Source.
     
  15. sarita78

    sarita78 Newbie

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    I was rx'd baclofen last year and took it for a good many months. I found it helped her sleep in large quantities but didn't do much else. I tried phenibut for the first time yesterday and was extremely impressed! She had read how it is closely related to baclofen. In her experience she did not see the similarity. Phenibut not only produced benzo-like calmness, it lasted for hours!!! And I was able to sleep for 10 hours. That in and of itself is a huge feat for swim. She has suffered insomnia for over 17 years with very few things helping her. Very impressed with phenibut.

    It should be noted I took phenibut with tramadol. Also when I was taking baclofen it was in conjunction with dangerously high dosages of tramadol as well.
     
  16. imyourlittlebare

    imyourlittlebare Palladium Member

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    SWIM always wondered why and how phenibut was considered a nootropic? Its only in Russian literature where they propose this idea. And since it does work similarly to Baclofen, I know that BAC causes severe memory deficits in rats (The GABAB receptor antagonist CGP36742 attenuates the baclofen- and scopolamine-induced deficit in Morris water maze task in rat). Not to mention that BAC has aversive qualities similar to lithium chloride (from original research I am presenting at society for neuroscience this year)
     
  17. imyourlittlebare

    imyourlittlebare Palladium Member

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    The GABAB receptor antagonist CGP36742 attenuates the baclofen- and scopolamine-induced deficit in Morris water maze task in rat is by Y Nakagawa

    As far as original BAC research goes, the poster wont be available for a little while. But theres a world of research on the negative effects of BAC on memory and the positive ones of GABA B antagonists. A good starting place is the above article.
     
  18. LaidBack

    LaidBack Newbie

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    Would the effects of Phenibut be increased if one injected it ? SWIM noticed that the bulk powders he has dissolve very well in water and are not cut with extraneous "stuff" like the pills. Is there any evidence that this mode of administration would work better? Please note that I'm not recommending this. This simply for curiosities sake.
     
  19. adelante

    adelante Newbie

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    is phenibut good for sex?
     
  20. DiabolicScheme

    DiabolicScheme Titanium Member

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    I had aprevious experience report, well come to find out the product was a complete farce and seemed to be reported as simply a GABA product.

    I feel the need to make people aware that this product can turn on You very quickly if caution is not taken when dosing. Its not just the withdrawal symptoms you need to worry about.

    I have since tried a different brand that yielded a much different effect, I have two experiences to share one was great, the 2nd went horribly bad.

    EXPERIENCE 1 - THE GOOD ONE
    SWIM began taking phenibut two weeks ago and wanted to get a good nights sleep, I took 1,800MG his first time. Took approx. 2 hrs before it took effect but man was it amazing. I felt incredibly relaxed, alcohol/xanax like feeling but with no brain fog. SWIM experienced this feeling for about 3-4 hours because he liked the feeling he decided not to go to sleep right away. Seriously, this product was single handedly THE BEST anti-anxiety medication I have ever had. Clear headed, calm, and relaxed.

    EXPERIENCE 2 - THE BAD ONE

    I tried it again another day, took the first dose of about 1.5MG at around 2PM during the day since I was going out to a birthday party he didn't want social anxiety to creep up.

    This kicked in perfectly at 4PM when the party started, I would also like to add that he took 6G of Bali Kratom as well to make SWIM more sociable. I was completely relaxed, nothing could bring me down and it wasn't strong enough to make me want to dose off.

    I got home around 6PM and this is where it took a turn for the worst, thinking the stuff was starting to wear off [Kratom perhaps made SWIM think it was since Kratom is a slight stimulant for SWIM] he redosed with another 1.2G.

    Everything went fine until 8PM came around, I felt completely drunk off his ass. I became dizzy and slightly nauseous. At this point the only thing I could do is lay in the bed because he pretty much could no longer function. Best way I could describe this feeling is being WAY too drunk and getting the "spins" with the added benefit of cognitive functions being way too clear. In other words, I remember it clear as day.

    9PM came around and SWIM threw up all his food in his stomach to the point there was nothing left and I was dry heaving.

    9:30PM was a repeat of throwing up, but there was nothing in SWIM's stomach thus dry heaving.

    ..30 minute increments until about 6 in the morning I was visiting the toilet, SWIM probably heaved about 10 to 15 times and in between these I was nodding off but due to fear of what was happening SWIM fought to stay awake which I did so successfully most of the night.

    By 10AM the next day the dizziness FINALLY subsided, but the effects were not over with I could still feel the sensation of the calmness this stuff gives in proper doses. SWIM slept until 8PM that night and woke up to go to work.

    It wasn't until 11PM when the stuff finally completely wore off. On the bright side SWIM never experienced the supposed horrible after effects when the stuff wore off, in fact SWIM experienced more of an afterglow in which his mood seemed much better the following day after dosing.

    Some suggestions:
    - DETERMINE yous dosage and don't jump right in and take more than 2 grams or you could be vomiting drunk for 14 hours and remember it all of it clear as day. Which SWIM's opinion makes it 10x worse. As it has been said its easier to increase a dose than it is to decrease a dose once You has already taken it.

    - Phenibut is tricky, don't assume because it hasn't kicked in 30 minutes after taking it that You needs to take more. WAIT at least 2 to 3 hours before determining that You needs more, even then increase doses SLOWLY.


    - I do not recommend one to REDOSE until at least 24 hours have passed since the last dose as this stuff will build up and doesn't wear off quickly like say Xanax.

    - If You has a addictive personality, please avoid this product. This product in SWIM's opinion should not be taken lightly just because it is legal.

    Be SAFE SWIMMERS!