Piperazines: New Novel, Potent, & Selective Dopamine Reuptake Inhibitors...! (?)

Discussion in 'Research Chemicals' started by Richard_smoker, May 10, 2006.

  1. Richard_smoker

    Richard_smoker Gold Member

    Reputation Points:
    Sep 19, 2005
    from U.S.A.
    Development of Novel, Potent, and Selective Dopamine Reuptake Inhibitors through Alteration of the Piperazine Ring of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909)

    Dorota Matecka, Richard B. Rothman, apubs.acs.org_images_entities_dagger.gif Lilian Radesca, Brian R. de Costa, Christina M. Dersch, apubs.acs.org_images_entities_dagger.gif John S. Partilla, apubs.acs.org_images_entities_dagger.gif Agu Pert, apubs.acs.org_images_entities_dagger.gif John R. Glowa, Francis H. E. Wojnicki, and Kenner C. Rice*
    J. Med. Chem., 39 (24), 4704 -4716, 1996. jm960305h S0022-2623(96)00305-6

    Laboratory of Medicinal Chemistry, Building 8, Room B1-23, National Institute of Diabetes and Digestive and Kidney Diseases, and Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, and Clinical Psychopharmacology Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224
    Received April 24, 1996 apubs.acs.org_images_entities_cross.gif
    Sorry, I don't have access to the full text--must be an obscure journal--however, I thought it might be of interest to those who were previously discussing DAT protein (messed-up in cocaine addiction) and to all you piperazine fanatics! -Dick