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Anal use - Plugging / Rectal Tramadol?

Discussion in 'Tramadol' started by Cuberun, Sep 18, 2007.

  1. Cuberun

    Cuberun Gold Member

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    Hi, was wondering if it's possible to plug tramadol to overcome naseua.
    SWIM has some Ultram capsules 50mg each. No syringe unfortunately but has read about experiences of plugging other things in capsules.

    SWIM can ingest 350mg of tramadol no problem in a day but after a while he starts feeling a bit queasy even though padded with or without food.

    Yes, tramadol doesn't work for some but it works very well for SWIM, so no discussion about this please :)

    Anyone have any knowledge on this?

    Thanks
     
  2. trptamene

    trptamene Platinum Member & Advisor

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    I really can't say either way whether IB (intrabumum) will work, but have read that it if will work orally it will work rectally as well.

    tramadol works we.l for swim too, but he lost his prescription for it. He took ultram nearly daily at the around swiys dose (250-400mg daily) for about a year. He sometimes felt the queasyness swiy talked about but mostly he experienced heartburn/acidic stomach problems after about 10 months of this, he hoped this would stop after he stopped taking it but 4 months later he still has these problems.

    Daily this probably would not be a good idea, but if one is asking just for recreational value that does not occur often then it would be a good idea if this did work and there were no ill side-effects.

    I am curious if anyone has any experience also.
     
  3. sarbanes

    sarbanes

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    Inferior method as it bypasses desirable 1st pass hepatic metabolism, and is rather irritating to perianal area at theraputic doses. But maybe will avoid the neausea?
     
  4. Cuberun

    Cuberun Gold Member

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    Thanks for the replies. Yes, SWIM doesn't get any naseua now once he's used to it. That also means it's time to stop though unfortunately :)

    For next time it seems plugging isn't an option though.
     
  5. jayjohnson81

    jayjohnson81 Titanium Member

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    Don't worry, you should still practice plugging with water or your favorite beer (just a couple plugs - you'll get ass-drunk real fast) so your ready for when you need to plug something for real.

    (Sorry... I'm wasted.. )
     
  6. Intoxicating Dreams

    Intoxicating Dreams Silver Member

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    I am new here and finding the information fasinating and of superior quality (well the beer plug post above made me laugh pretty hard, even though I have done the wine enema thing once). Anyway, what is Tramadol? SWIM used to snort adderall, and other stimulants like it, but can no longer access it and it made her art much more enjoyable. Would tramadol or Ultrim make a good substutite. Do they require perscriptions? Thank you for any suggestions.
     
  7. trptamene

    trptamene Platinum Member & Advisor

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    UTFSE(use the forum search engine)

    in general do not post questions that have been answered anywhere else on this site and do not add any information that is already on this site; this is good for keeping down all the noise and I think it may also keep the monthly costs down(maybe a mod can clarify this?)

    from erowid
    it is Rx in the US
     
  8. fiveleggedrat

    fiveleggedrat Palladium Member

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    Swim has a good amount of tramadol. Problem is, for some unknown reason, it just flat-out stopped producing euphoria. Sedation is still there in bucketloads, but the euphoria is gone. Before anyone asks, there is ZERO physical tolerance. Only thing Swim is tolerant to regularly is marijuana. Opioids are consumed every few weeks. Swim has even taken several month breaks and came back to tram with the same issue.

    Swim's real question is this: Even though rectal tramadol sounds like it would fail due to lack of 1st pass hepatic metabolism, is there possibility it will create euphoria? Swim used to believe that metabolite M1 caused most euphoria. Swim has tried every single potentiating combo he could thing of, most of them only increasing sedation and nothing else.

    Could tramadol rectal act differently than oral? Perhaps Swim's body has developed some sort of "anti-tramadol" response? Could rectal be a way to pass it? And why could it have stopped being euphoric? Did Swim's brain just adapt to the tramadol and now prevents it from being euphoric?

    Regardless of questions, Swim thinks he will attempt rectal tramadol soon. An experience report will follow.
     
    Last edited: Sep 24, 2008
  9. Mish

    Mish Silver Member

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    SWIM was just wondering if plugging Tramadol actually will increase it's effect (i.e. require a lesser dose to achieve effects of a higher oral dose)

    SWIM never gets nausea on Tramadol, but the oral come up seems to take a long time and SWIM finds himself going through a fair amount of Tramadol simply because the effects aren't quite strong enough. Would plugging help with reduction of dose to reach desired effects, or is the bioavailability high enough orally that it won't make any difference...?
     
  10. soma

    soma

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    Erm, isn't the M1 metabolite responsible for most of the effects of Tramadol (being that it has roughly 1000x the affinity for the Mu opiate receptor). In theory, that would mean that by injesting it anally, you would bypass the 1st pass metabolism and therefore not create any of the M1 metabolite, thus killing any opiate effect of tramadol.
     
  11. StopDropNRoll

    StopDropNRoll Newbie

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    Did you take any medicines that act on the CYP2D6 enzyme? These inhibitors include SSRIs, some antihistamines, some antipsychotics, cimetidine and some other mainstream medicines. If so, what is happening is the Tramadol is not being converted to M1, which is the metabolite that produces the euphoria. M1 metabolite binds to opiate receptors 100x greater than tramadol.

    If you are looking for the euphoria side effect, the CYP2D6 inhibitors need to be out of your system. *However some of the medicines should not be discontinued abruptly, such as Prozac, etc.*

    Also--if you are indeed on any of the inhibitors, the risk of serotonin syndrome increases with this medicine.

    I take Prozac, and I combined it with 400mg Tramadol one time. I was having tics on the right side of my face, vocal tics where it appeared that I had a speech impediment; also I suffered chest pains. I felt like I was on the verge of a seizure or heart attack. It was not pleasant at all.

    I also believe that smoking cigarettes activates some of the side effects such as nausea and the muscle spasms, as nicotine temporarily increases dopamine and acetylcholine which are both neurotransmitters involved in the muscular system.

    Hope this helps. See a list of "CYP2D6 inhibitors" for more information.

    *There is well documented case histories of tonic-clonic seizures occuring in people who abuse Tramadol. Please be very cautious as always, and understand the risks someone takes when they are choosing to use high doses of this medicine.*
     
  12. LostAllFeeling

    LostAllFeeling Newbie

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    tramadol is not a drug that has any real useful properties unless metabolized through the stomache and etc. some people report effects from snorting, but they are always extremely minute and commonly it is regarded as a waste unless taken just as a pill. in theory one could parachute tramadol or crush it up and injest said powder. it would probably hit harder and not last as long which for tramadol would be a huge plus. SWIM apologizes that he cannot offer any advice to get over the nausea. Tramadol is a very nauseating drug if used in high enough dosages to produce a recreational effect. SWIM would move on to something more tolerable on the stomache, or something that actually could be snorted or plugged. best of luck
     
  13. Dr_Janus

    Dr_Janus

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  14. KingTussin

    KingTussin Silver Member

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    I tried a new thought up method today for plugging tramadol, it worked great. I used half a gel cap, some lub, and my finger.. Anyway I put the tramadol into a half gel cap then held my index finger on open side, holding the powder in. I then covered it with lub, as I held onto it with my thumb and index finger. I than laid down on my side and stuck it up there. I must say, this was very easy. Way better than using a turkey baster lol. No nausea, still feeling very calm, and it kicked in VERY fast! I'll never abuse this drug, because it makes me too itchy, once in awhile is fine though.
     
  15. Xanahalf

    Xanahalf Silver Member

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    This is a 3 year old thread. All of the science behind plugging tramadol says that it should be a significantly weaker trip than using it orally. None of the precious o-desylmethyltramadol (i think thats right) is produced that way and that metabolite is MUCH stronger than the tramadol itself.

    What effects do you get from plugging? What dose? How does it compare to similar oral dose?
     
  16. KingTussin

    KingTussin Silver Member

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    Well, first off Tramadol doesn't cause a trip for me, just a long high. In many other forums people say plugging tramadol increases the effects by a small margin, just slightly better than orally.

    My experiences plugging tramadol.
    -It kicks in much faster.
    -The sedation is increased.
    -It doesn't last as long as orally. 150mg lasts 5-6 hours, as orally lasts almost all day.
    -No nausea.
    -Doses like 100mg plugged feels like 150mg orally.
    -Increases euphoria.
    -Weight lifting seems much easier.
    -Less itching.

    I've looked at many other forums about this topic and they think the same thing. Google it, you'll see what I'm talking about.
     
  17. Xanahalf

    Xanahalf Silver Member

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    Hmmm you appear to be correct. Many anecdotes claim that plugging tramadol is stronger - ill have to try it myself one of these days... Maybe the o-desylmethyltramadol is somehow metabolized out of the blood stream? It's odd because i was under the impression that codeine and tramadol had fairly similar mechanisms of action and most people say that rectal codeine use is a waste of time.

    Also the fact that IV tramadol exists in a medical setting points to either the desylmethyltramadol being created when tramadol is in the blood stream (as opposed to during first-pass hepatic route), or desylmethyltramadol is much less important to the tramadol experience than people think.

    Anybody who actually knows what they are talking about have anything to share? My knowledge of metabolism is basically limited to what i have learned from drug web sites haha

    UPDATE: I plugged 2, 50mg tramadol. Emptied the capsules, mixed with water, oral syringe up the bottom - powder dissolved easily. I felt the effects quickly but I sadly did not find the effects to be stronger than normal - if anything it felt weaker. Hard to use this test as anything close to proof because I was kinda EXPECTING it to be weak and obviously expectation plays a huge role... I wont be repeating this RoA tho - found it did not give as strong effects as oral use and much shorter acting. Fast onset but obviously no "rush" or anything
     
    Last edited: Jan 28, 2013
  18. chefJIMBOmetalDRUMMER

    chefJIMBOmetalDRUMMER Newbie

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    I'm an extremely experienced opiate user with a vertu t high tolerance for all opiates. I get 150 of the round 50mg tramadols a month, and have experimented with all possible ROAs. First off, let me say that I AM one of those for whom this drug can work amazingly... producing euphoria akin to h, and a speedy-like high that reminds me of amphetamines. (Very much like the speedy feeling I can get from bup if I get the dosage right)

    I'd take as much as 400mg orally at a time, but usually not more than a gram per day. (which I realize now, was very dangerous as it could easily cause a seizure at those doses). I would get very, very high off of tram that way.

    Then I'd read about how you can only convert so much of it to the stronger opiate during digestion, so I started doing 100mg to start, and then 50mg every half hour. I noticed a slight advantage as to what I was getting out of a dose when used that way, but l wouldn't actually get high for hours.

    Today I tried plugging tramadol. I plugged 400mg by dissolving in water, using an oral syringe to get up there. This kicked in very fast... like in as little time as 5 minutes, and due to the fact that it would miss the first part of digestion, I was actually expecting very little, so I'm certain it wasn't placebo. I got more intense euphoria n I'd ever gotten from trams, some mild sedation, not much speediness, but TONS of itching. To the point of being very bothersome. Even after benedryl. .. this level of itchiness was only matched by a few IV - "H" experiences at high doses, and only surpassed by drinking an entire bottle of tussionex (sp?). Which is a hydrocodone suspension cough syrup that also contained a small amount of decongestant. I would NEVER have thought hydrocodone/vicodin would have been one of the best (and unfortunately the itchiest) opiate experience I'd ever had. (Granted, tussionex is a very strong concentration of hydrocodone, and I would always down the entire prescription.) And I've tried them all, from hydromorphone, to oxymorphone, to fentanyl, etc..

    I mention this because this tramadol high (plugging 400mgs) is VERY close to as good. I know basically everyone, including forum moderators say that it should be the weaker ROA due to skipping the first step in digestion, where that stronger o'deso-whatever is created.... but I swear to you all, that is incorrect. I am prescribed trams, use them often, and know exactly what the same dose would have done orally, and this blows it away. . And just to reiterate, it is also a different high due to more euphoria, less speediness, slightly more sedation, and LOTS more itching.
     
  19. that oneguy

    that oneguy

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    Ill try out plugging this drug I've taken four orally so far and don't feel any if the effects (I'm in treatment for heroin abuse and currently taking 160mg of methadone so my tolerance is pretty good/horrible however you'd like to view it) I'm trying tramadol to see if it'll have Any effects as I've shot a whole gram of Diesel in one syringe (yes very stupid to do that I know don't try it yourself) and felt literally nothing more than a brief body rush like morphine for a few minutes before it completely disappeared,I know it was decent quality because my friend shot a single point and nodded out for the next few hours so while yes I'm trying to quit my drug use I still struggle with wanting to feel the high again that makes you happy and nothing is that bad anymore.So here's hoping it not being a true opiate will work around my methadone treatment.