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Drug info - Research Chemicals Index - Synthetic Cannabinoids

Discussion in 'Cannabinoids' started by Shampoo, Jul 24, 2009.

  1. Shampoo

    Shampoo entity of sorts Staff Member

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    Synthetic cannabinoids are a structurally diverse group of compounds that act as cannabinoid receptor agonists. Some of these compounds produce intoxicating effects similar to those of the phytocannabinoids found in plants of the genus Cannabis, while others produce varying levels of euphoria, intoxication and analgesia. Despite their functional homology, many research chemicals of this class bear little structural resemblence to naturally occurring cannabinoids. Synthetic cannabinoids are typically active in the very low milligram range and either smoked (alone or as part of a smoking blend mixture) or taken orally. Given the potency of these compounds, use of appropriate weighing apparatus is essential to minimize the risk of overdose.

    Please help to expand our understanding of this class of psychoactive substances by contributing to the threads highlighted below, and recognizing posters that have made useful contributions by awarding positive reputation.

    Column 1 Column 2 Column 3 Column 4 Column 5 Column 6 Column 7
    0
    Cannabinoid​
    Drug Info​
    Drug Experiences​
    Tagged Threads​
    Documents​
    Image Gallery​
    1
    JWH-018​
    2
    JWH-073​
    3
    JWH-081​
    4
    JWH-200​
    5
    JWH-250​
    6
    AM-694​
    7
    CP-47,497​
    8
    CP-55,940​
    9
    HU-210​
    10
    WIN-55,212-2​
    11
    JWH-007​
    12
    JWH-015​
    13
    JWH-017​
    14
    JWH-019​
    15
    JWH-203​
    JWH-203 Info​
    JWH-203 Experiences​
    16
    JWH-210​
    17
    JWH-307​
    18
    JWH-398​
    JWH-398 Info​
    JWH-398 Experiences​
    19
    AM-2201​
    AM-2201 Experiences​
    20
    CB-25​
    21
    CB-52​
    22
    SR-18*​
    SR-18 Experiences​


    * Note: SR-18 is a colloquial term for this compound and does not appear in any patent documentation or peer reviewed scientific literature. This compound is a close homologue of the better characterized compound JWH-250.

    ______________________________________

    Related Research Chemical Indices:

    Phenethylamine RC Index
    Tryptamine RC Index
    Piperazines RC Index
    Miscellaneous RC Index
    Unidentified RC Products Index
     
    Last edited by a moderator: Oct 12, 2010
  2. osirisx

    osirisx Newbie

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    Re: Research Chemicals Index- Cannabinoids

    JWH-007
    JWH-122
    jwh-133
    AM -630
    AM-694
    AM-1241
     
  3. Shampoo

    Shampoo entity of sorts Staff Member

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    Re: Research Chemicals Index- Cannabinoids

    JWH-122 is mentioned in "The Cannabinoid Receptors", by Patricia H. Reggio- noted as having a very high affinity (Ki of 0.69 +/- 0.05 nM) for the CB1 receptor. This is the only place in which this compound appears outside of the Huffman papers.
     
  4. Drats

    Drats Gold Member

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    Re: Research Chemicals Index- Cannabinoids

    SWIM tried to use the search engine and Google, but did anyone found an experience report with JWH 122 or JWH 210? The substances are getting available through several vendors, so SWIM is concerned about the high affinity, which would indicate the dosage is extremly low and the risk of overdosages are extremly high. Also no information could be found on duration and else.
     
  5. Phenoxide

    Phenoxide Super Moderator Staff Member

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    Re: Research Chemicals Index- Cannabinoids

    The index at the top of this thread has now been updated to include discussion of cannabinoids that has occurred since the last update 12 months ago. Please contribute to the highlighted threads and also help to keep this index up-to-date by highlighting new drug information and experience threads as they arise.
     
  6. jeremysdemo

    jeremysdemo

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    is there any way to get an analog map or diagram here of these?

    for example JWH-081 is an analog of JWH-018.

    jerm
     
  7. Phenoxide

    Phenoxide Super Moderator Staff Member

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    Simply put no. Analogue law is deliberately vague and therefore left open for interpretation by the courts. There is no definitive mapping of 'X is legally considered analogous to Y' because of this ambiguity. The definition of analogue will also vary by jurisdiction (if a definition is even offered at all). If a compound shows cannabinoid receptor activity and has recreational psychoactive effects then a case for analogy in the broadest sense could always be made.
     
  8. jeremysdemo

    jeremysdemo

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    most of the cases I have been following are using the analog law for substances with "structural similarity".

    if the government paid PHD's can look at them and determine that from their molecular shape I'm sure people in the private sector have the ability too.

    jerm
     
  9. Phenoxide

    Phenoxide Super Moderator Staff Member

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    You don't seem to comprehend what I am saying. "Structural similarity" is a not a well defined chemical term. It is not a magical definition that all chemists immediately reach a consensus upon. I could draw up a far from complete list of what I consider to be structural analogues (both known and theoretical) of substance X, but my list wouldn't necessarily match those of other chemists, and more importantly it may not match the interpretation of the courts. Such a list would therefore create false assurances over the legal status. It's open to interpretation and the courts have the final say on the matter. There is no "right" answer.

    If there was a definitive answer to what you're asking for then analogue law would be without purpose. It exists is to create this ambiguity and thereby gives the courts some flexibility to prosecute where they know an individual is skirting the law (and let's face it, they know the "designer drug" trade isn't legitimate) but would otherwise get by on a technicality. The reach of analogue law only becomes clear when it is tested in the courtroom. Anything before that stage would be speculation.

    Let's not forget that the courts are also mindful of intent. In the context of an unregulated, untested chemical being obviously sold for human consumption (no matter how it is packaged), the courts are likely to side with the prosecution if they have even a weak case for analogy. Such a case could be easily created for most of the cannabinoids being analogous to something on the controlled substances list of the state or federal government.
     
  10. trigger1313

    trigger1313 Newbie

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    So are blend producers just playing roulette with the cops. Have talked to several shops in Texas and have a intrested group, but concerned with the laws. Seems the analog act is a catch all.
     
  11. syntheticdave

    syntheticdave

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    I'v gone about to create a new table, containing 32 additional cannabinoids which at the time of the original post had either not yet been marketed or synthesized. The table below contains all of the cannabinoids mentioned in the original post, with some of the links being updated.

    Enjoy
    SyntheticDave

    Column 1 Column 2 Column 3 Column 4 Column 5 Column 6 Column 7 Column 8
    0
    Cannabinoid​
    Drug Info​
    Drug Experiences​
    Tagged Threads​
    Documents​
    Image Gallery​
    1
    2
    2NE1
    2NE1 Experiences
    3
    4
    A-834,735
    [/CENTER]
    A-834,735 Experiences
    [/CENTER]
    5
    6
    A-836,339
    A-836,339 Experiences
    7
    8
    AB-001
    [/CENTER]
    AB-001 Experiences
    [/CENTER]
    9
    10
    AB-034
    AB-034 Experiences
    [/CENTER]
    11
    12
    AKB48
    [/CENTER]
    13
    14
    5F-AKB48
    [/CENTER]
    15
    16
    AKB-NI
    [/CENTER]
    AKB-NI Experiences
    17
    18
    AM-694
    [/CENTER]
    19
    20
    AM-1248
    [/CENTER]
    21
    22
    AM-2201​
    23
    24
    AM-2233
    [/CENTER]
    25
    26
    BAY 38-7271
    [/CENTER]
    BAY 38-727 Experiences
    27
    28
    BB-22
    [/CENTER]
    BB-22 Experiences
    [/CENTER]
    29
    30
    CB-25​
    31
    32
    CB-52​
    33
    34
    CP-47,497​
    35
    36
    CP-55,940​
    37
    38
    EAM-2201
    [/CENTER]
    39
    40
    HU-210​
    41
    42
    JTE-907
    [/CENTER][/CENTER]
    JTE-907 Experiences
    [/URL]
    43
    44
    JWH-007​
    45
    46
    JWH-015​
    47
    48
    JWH-017​
    49
    50
    JWH-018​
    51
    52
    JWH-019​
    53
    54
    JWH-022
    [/CENTER]
    JWH-022 Experiences
    55
    56
    JWH-030
    [/CENTER]
    JWH-030 Experiences
    57
    58
    JWH-073​
    59
    60
    JWH-081​
    61
    62
    JWH-122
    [/CENTER]
    63
    64
    JWH-147
    [/CENTER]
    JWH-147 Experiences
    65
    66
    JWH-182
    [/CENTER]
    JWH-182 Experiences
    67
    68
    JWH-200​
    69
    70
    JWH-203​
    71
    72
    JWH-210​
    73
    74
    JWH-250​
    75
    76
    JWH-251
    [/CENTER]
    77
    78
    JWH-307​
    79
    80
    JWH-370
    [/CENTER]
    JWH-370 Experiences
    81
    82
    JWH-398​
    JWH-398 Experiences
    83
    84
    MAM-2201
    [/CENTER]
    85
    86
    MN-25
    [/CENTER]
    MN-25 Experiences
    87
    88
    NNE1
    [/CENTER][/CENTER]
    NNE1 Info
    NNE1 Experiences
    89
    90
    PB-22
    [/CENTER]
    91
    92
    5F-PB-22
    [/CENTER]
    93
    94
    RCS-4
    [/CENTER]
    RCS-4 Experiences
    95
    96
    SR-18​
    SR-18 Experiences
    97
    98
    STS-135
    [/CENTER]
    STS-135 Experiences
    99
    100
    UR-144
    [/CENTER]
    101
    102
    5F-UR-144
    [/CENTER]
    103
    104
    URB-597
    [/CENTER]
    105
    106
    URB-754
    [/CENTER]
    URB-754 Experiences
    107
    108
    WIN-55,212-2​

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