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Combinations - Safety of Alcohol and Viagra

Discussion in 'Alcohol' started by Nature Boy, Feb 7, 2007.

  1. Nature Boy

    Nature Boy Gold Member

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    Is it safe to drink alcohol while using viagra? List any significant side effects, possible dangers etc.
     
  2. Jatelka

    Jatelka Psychedelic Shepherdess Platinum Member & Advisor

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    Interesting question NBL: A swift search (all SWIJ has time for ATM) finds only this abstract:

    "No adverse hemodynamic interaction between sildenafil and red wine"
    (LESLIE Stephen J, ATKINS Graham, OLIVER James J, WEBB David J)

    Our objective was to investigate the hemodynamic interaction between sildenafil and red wine. Sildenafil citrate (Viagra), a phosphodiesterase type 5 inhibitor, is an effective treatment for male erectile dysfunction that potentiates nitric oxide-mediated vasodilation. Alcohol is a commonly used recreational substance with complex vascular effects, which may, in part, be mediated by nitric oxide. Thus there is potential for an adverse hemodynamic interaction. Methods: Eight healthy men received either 100 mg sildenafil, alcohol (750 mL red wine, 13.5% by volume), or the combination, in a 4-way, double placebo-controlled, randomized crossover study. Blood pressure, heart rate, and cardiac index were measured every 15 minutes up to 180 minutes. Results: Results are expressed as mean ± SEM. Red wine increased cardiac index (by 15% ± 8%, P = .04) and heart rate (by 27% ± 5%, P <.0001). Mean arterial pressure initially increased by approximately 5% and then fell by a maximum of approximately 7%. Sildenafil reduced peripheral vascular resistance (by 24% ± 8%, P = .03) and mean arterial pressure (by 7% ± 3%, P =.03) with no effect on cardiac index or heart rate. Conclusions: There is no clinically important hemodynamic interaction between sildenafil and alcohol (red wine).

    The study design was somewhat artificial and may not have reflected typical use, because the men were young and did not exercise or have intercourse following administration of the wine and/or sildenafil.

    SWIJ also adds that 8 people is hardly a rigorous study!

    The authors conclude that " More research needs to be done"
     
  3. Nature Boy

    Nature Boy Gold Member

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    Thanks for the article Jatelka. It's rather inconclusive as the author points out however. Any other information people can add would be appreciated whether it be anecdotal or scientific.
     
  4. Nagognog2

    Nagognog2 Newbie

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    Anecdotal cultural trends would seem to indicate that people have been drinking alcohol and popping Viagra since it hit the marketplace. After all, alcohol and sex pretty much go hand-in-hand in our society. If this combination was dangerous to any signicant degree, no doubt we would have heard about it.
     
  5. iTsS JuSt J

    iTsS JuSt J Newbie

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    The only danger I can think of when combining Viagra and Alcohol is a drop in blood pressure. I know that Viagra dilates blood vessels causing blood pressure to drop and that a large consumption of alcohol will do the same. So when combining the two you should be aware of the dangers of your blood pressure "bottoming out". Bottoming out can cause you to pass out or possibly die. I don't know the exact amount of alcohol or Viagra it would take to do that, but I'm sure a few drinks and one pill wont do it unless you only weigh approx. 100lbs.

    But also I'm no doctor so don't quote me on this. I just recommend doing some research on both Viagra and alcohol and its effects on blood pressure to get a more accurate answer.
     
  6. old hippie 56

    old hippie 56 Newbie

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    A few beers and a Viagra equals one helluva of a headache. Tried it without the beer, no headache.
     
  7. Myzel

    Myzel Silver Member

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    I know a guy that is in his 50's and got a pace maker, lots of other heart problems and drinks like a fish.. Such as a bottle of crown a night then pops 2-3 Viagra then has sex for 3-4 hours.. I have seen him pop the Viagra and the drinks but didn't stick around for the sex.. So is it safe ?Probably not but this dude's still alive and drinking...
     
    Last edited: Feb 20, 2007