separate mitragynine from kratom resin?

Discussion in 'Kratom' started by bassdude, Aug 5, 2005.

  1. bassdude

    bassdude Newbie

    Reputation Points:
    Aug 3, 2005
    Does anyone know the process of separating the mitragynine alkaloid
    from kratom extract. How do you refine it or separate the alkaloid from
    the plant waxes, oils and tannins? I use and iso-2 to extract the
    resins using ethyl alcohol but I need to know how to process it
    further. Does the process that you use for salvia d. which is naptha
    which absorbs the plant waxes and tannins and leaves the salvinorum A
    work with kratom? I need a reply from someone who really knows his or
    her sh#t. Thanks
  2. fcknut

    fcknut Newbie

    Reputation Points:
    Jun 4, 2005
    seperating out alkaloids from the resin you get from a simple
    extraction is going to be extremely tricky for someone who does not
    really know what they're doing.

    you could mulch it up in hydrochloric acid for a few days, then wash
    with ether or something similar. Then add sodium hydroxide until the
    mixture was sufficiently basic, then extract with ether again to give
    you a mixture of alkaloids - be prepared for a loss in yiled though,
    especially if you don't understand the principles and haven't had any
    experience with this kind of thing.

    for further purification I guess you could look at chromatography on
    silica, but if you don't know what you're doing then I would just leave
    it as it is or you're going to waste a lot of material on a fairly
    steep learning curve.

    Also, the fact that kratom contains a number of potentially active alkaloids is going to make it all the more difficult