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Experiences - Smoking Loperamide, also DXM

Discussion in 'Opiates & Opioids' started by Freedom of Mind, Jun 11, 2009.

  1. Freedom of Mind

    Freedom of Mind Silver Member

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    Loperamide is a synthetic opioid-receptor type drug, Imodium is one brand name that sells it. If taken orally it gets broken down before reaching the blood brain barrier so opiate effects are not given. However alternative methods could be used for effects similar to other opiate painkillers by smoking it.

    I was thinking about another topic then dreamt something.
    I did an alcohol extraction of ten pills Loperamide, each of them 2 mg. After dissolved in alcohol liquid filtered through coffee filter, then allowed to dry, it left a sticky yellow substance. SWIM put some of this on weed in a bowl, felt very relaxed and euphoric after just one or two hits, 50 minutes still on the same bowl spreading hits out as he has very euphoric buzz going stronger. I will try again to be sure, but he is pretty sure smoking Loperamide allows it to cross the Blood Brain Barrier. I took the DXM less than 10 minutes before, and started smoking the extract shortly after. The effect were felt right away and kept getting stronger as I smoked more over time even before the DXM would of began taking effect. I even dreamt that he was feeling the effects were active CNS while writing this post.

    3:50: 20 DXM tablets oral are taken (300 mg)

    Sometime before 4:00 SWIM packs a bowl of weed and scrapes up some yellow Loperamide goo, puts some on the weed and mixed in, I feel very good buzz after two hits and thinks the weed alone wouldn't have such an effect, within a mintue of hitting the bowl feels what could be described as an opiate type buzz

    4:16 smoking, feel relaxed and euphoric

    5:08: feeling good buzz getting stronger, still smoking the same bowl and spacing hits

    5:22 still getting more buzzed, takes another hit although feeling good already, dxm feeling like its starting to kick in and potentate the experience further.

    I have no idea if one could die were they to do that and thinks no one should do what I dreamt without research first.
     
    Last edited: Jun 11, 2009
  2. killersnowman

    killersnowman Silver Member

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    this is interesting... can anyone confirm this? also, do You have any sort of opiate tolerance or are You a 'clean' slate?
     
  3. Freedom of Mind

    Freedom of Mind Silver Member

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    I have some opiate tolerance, but not very strong compared to what some people have. SWIM enjoys opiate use, but makes sure to avoid using them to often as I know people who have gotten addicted through overuse.
     
  4. killersnowman

    killersnowman Silver Member

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    has You tried smoking it with out the weed to try to isolate the effects?
     
  5. Freedom of Mind

    Freedom of Mind Silver Member

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    No, when SWIM gives it another try he will post on the effects here, more experimentation is needed to come to any conclusive results.
     
  6. Freedom of Mind

    Freedom of Mind Silver Member

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    SWIM soaked two cigarettes in an extract made from 25 pills (50 mg), don't know how many mg soaked into some ciggs but it was less than 10 mg each. SWIM and a friend smoked one each and both noticed a mild euphoric buzz. My friend wanted to smoke another so we smoked one more each, I don't really remember very good how much the second one enhanced it but I remember being paranoid about dosage while doing the second cigg. The buzz was stronger than after smoking the second, but still overall not very strong if swim recalls correctly, the paranoia was probably due to having read posts online about being careful about dosage rather than the actual effects.

    The ciggs actually tasted pretty good and burned smoothly, both swim and the friend agreed on that. Seems like for smoking the amounts SWIM were it is more worthwhile to combo like I did before in order to make the effects feel stronger. I found the soaked ciggs more enjoyable than normal ciggs, but hassle of paying for a loperamide pack, dissolving, filtering, and letting it dry some to reduce volume is kind of a hassle. It might be a while before SWIM tries again as he has other things of interest to enjoy and experiment with, although eventually...
     
  7. Spucky

    Spucky Palladium Member

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    AW: Smoking Loperamide, also DXM

    Please do not forget that Loperamide is one of the strongest Opioids,
    it can kill very easy and quick!

    Swim add. the basic about Loperamide,
    please have a look!
     

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    Last edited: Jul 8, 2009
  8. Tussipax

    Tussipax Silver Member

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    It sounds great for SWIM too !
    But what kinda alcohol does I use ?
    How does SWIM dry loperamide solution extracted with alcohol ?

    SWIM soaks his cigg into the sticky yellow substance ?
    I need more information, it could be very awesome, please !!
     
  9. purplehaze147

    purplehaze147 Silver Member

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    Be carful when You mixes opiates and DXM. Both DXM and opiates can depress respiration at high enough doses, and there might be a synergistic effect.
     
  10. killersnowman

    killersnowman Silver Member

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    did swiyou experience any notable constipation after smoking said amount of loperamide? it is primarially used as an anti-diareal because it doesnt cross the blood brain barrier with any expediancy. from the research I has performed he is skeptical that smoking would have any greater effect of lipid soluability. it may however increase the plasma levels of the drug and thus cause an increase in transport just by there being more of said chemical. but the drug would eventually make its way to the opiod receptors in the gut and would probably still cause some pretty severe constipation. swims not sure that this would really have any real effect. the only possible theory would be that the pyrolysis of loperamide caused some change in the chemical to increase its lipid soluability. swim highly doubts it but maybe.

    You will have better results taking a whole lot of P-glycoprotein inhibitors like quinidine. this allows substances to cross the BBB in much greater volumes. so drink a lot of tonic water with grape fruit juice and then crush some black pepper and eat it. then wait 30 mins and do it all again but with your dose of loperamide. its easier, faster and more effective than extracting and smoking.

    everyone just wants to smoke stuff for no good reason....
     
    Last edited: Jul 10, 2009