For those who don't want to use rectal administration (and find snorting ineffective or painful), sublingual is more effective than oral, in SWIM's limited experience. Some of the substance will be absorbed through the oral mucosa in the mouth, similar to the way nicotine is absorbed from snuff or chewing tobacco. How: Dissolve 50mg or so in approx. 1ml of water. Put the liquid under your tongue using a teaspoon or needle-less syringe. keep it there -- do not spit, do not swallow, cup the bottom of your jaw so the water stays approximately under your tongue. Let it sit down there for 20 minutes, if possible (if it gets loose, let it swish around in your mouth rather than swallowing). When the taste gets to be so horrible you can't stand it (or you're gagging), swallow and chase with something good tasting. If anyone tries, pls report you's experience.