1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP
    Dismiss Notice

Effects - Sublingual Ritalin

Discussion in 'Concerta & Ritalin' started by MageYouLook, May 3, 2010.

  1. MageYouLook

    MageYouLook Silver Member

    Reputation Points:
    60
    Joined:
    Mar 30, 2010
    Messages:
    39
    Swim has tried ritalin by swallowing and sublingually.

    Swim has noticed that orally gives swim a lot of energy with a small euphoria.

    Swim has also noticed that taking ritalin sublingually even in 5mg amounts causes a very nice almost body orgasm for about an hour starting about 15 minutes after placing it under the tongue. taking 20 mg lasted 2 hours of strong euphoria.

    the interesting thing about sublingual that swim noticed was that it can make him sleepy or no change at all, he does not get any energy from it at any point and only has a strong euphoria.

    Swim is curious about: 1. why are the effects of oral and sublingual so different?

    2. has anyone else tried and noticed this?

    3. what causes the euphoria from sublingual? swim was under the impression that it must just be more dopamine related since norepinepherine has more to do with the energy burst that is absent.

    swim has not been able to find much useful information elsewhere and was hoping someone here would know. swim loves the euphoria from sublingual ritalin and recomends trying it in 10 or 20 mg as it is surprisingly and intensely pleasant.

    swim looks forward to swiys responses :)
     
  2. Kiddycrack

    Kiddycrack Silver Member

    Reputation Points:
    13
    Joined:
    Jan 10, 2010
    Messages:
    131
    SWIM has been taking Ritalin for about a year now and only uses on the weekend but he use to only take 20mg orally but has now been getting into higher doses. SWIM now usually takes 3 sublingual or parachute and then insufflates 1 or 2 and smokes some bowls that gets him the highest. SWIM from experience thinks that Insufflating(Snorting) Ritalin will get u the highest and gives SWIM a very nice euphoric, intense high.
     
  3. DextroClonazyCodone

    DextroClonazyCodone Silver Member

    Reputation Points:
    138
    Joined:
    Apr 2, 2010
    Messages:
    413
    SWIM experiences the same with Adderall (amphetamine salts). He gets very jittery if he simply swallows the pill, but has a very mellow, calm, euphoric mental high if dissolved sublingually. SWIM has searched for pharmacological answers, and has come up with nothing. He doesn't know why it is this way.
     
  4. doctordiddle

    doctordiddle Silver Member

    Age:
    37
    Reputation Points:
    7
    Joined:
    Nov 6, 2009
    Messages:
    5
    SWIM looked it up in a couple different pharmacology/pharmacy textbooks and found that there shouldn't be a difference in the effects of taking the same drug via different administrations of the drug (insufflation, sublingual, orally,...). The difference should be in the amount of drug that actually make it to your blood stream, and subsequently, the severity of he effects. So taking the drug different ways, shouldn't change teh types of effects SWIY feel, but by how much SWIY feels them. There just isn't a good reason to believe that the effects would be different (aside from differences that arise from varied doses). I'm not going to say that it's all in your head, but...


    In theory, oral administration goes through hepatic (liver) metabolism, and so a significant portion of the drug is broken down before it gets the chance to enter SWIY bloodstream (which causes the desired effects of the drug) - with Ritalin only 30% of the oral dose gets to your bloodstream.

    With sublingual administration supposes that since under the tongue is so vascular (lots of blood vessels), the drug will be absorber directly into the bloodstream. This would give a better effective dose - with Ritalin it's supposed to be close to 60% since a significant portion of teh dose will be inadvertently swallowed.

    Snorting should be similar to sublingual, but in theory could be better since there isn't the loss from swallowing (however, absorption in the vessels in the nasal cavity would be affected by how fine the R is ground, whether or not the powder actually made it to the blood vessels versus getting caught up in mucous or hair or what have you).

    All that said, SWIM has been using Vit R for a while now and tried the different methods and haven't found much of a difference, but has to believe that SWIY would get more R into SWIY's bloodstream snorting or sublingually.
     
  5. freedomf

    freedomf

    Reputation Points:
    -40
    Joined:
    Nov 4, 2009
    Messages:
    54
    swim believes that with concerta sublingually is the best method because oraly swim has no effect and to take concerta nasal is very difficult finally the most is swallad or stack in nose
     
  6. MageYouLook

    MageYouLook Silver Member

    Reputation Points:
    60
    Joined:
    Mar 30, 2010
    Messages:
    39
    Swim has tried snorting oral and sublingual. sublingual is definately very different. it does not give swim an energy boost. it only gives swim a great euphoria and almost even tires swim out.

    swim feels the normal effects from oral and snorting.

    swim has read about how different routes can cause an isomer selection. ritalin has a l and d isomer which have different effects. since there is no energy boost swim suspects it is turning the l to d, since they are mirrors of each other they can be flipped.

    swim could be way off of course but it is definitely a different and much better experience than oral or sublingual. could anyone give any info? any experiences?
     
  7. Kiddycrack

    Kiddycrack Silver Member

    Reputation Points:
    13
    Joined:
    Jan 10, 2010
    Messages:
    131
    SWIM takes 2 Ritalin IR everyday sublingualy and also gets a higher euphoria and focus compared to oral which has a milder effect with no euphoria. SWIM is currently prescribed 1 27mg GENERIC Concerta which is without the pump-release mechanism. He is going to take (attempt) his dose today sublingualy and post back here with results compared to oral.
     
  8. AlexaN

    AlexaN Silver Member

    Reputation Points:
    9
    Joined:
    Jul 8, 2010
    Messages:
    67
    Isn't it much more dangerous to snort Ritalin than to use it orally?
    I read it can damage the air passages / nasal tissues.
     
  9. MageYouLook

    MageYouLook Silver Member

    Reputation Points:
    60
    Joined:
    Mar 30, 2010
    Messages:
    39
    Swim thinks he understands better now. Swim has noticed similar euphoria when taking ritalin orally however orally really hinds the euphoria with the energy boost.

    sublingually swim has noticed he doesnt get any extra energy and if anything becomes lethargic from the euphoria.

    It could just be a better experience by removing the energetic distraction as the sublingual euphoria can be very nice if one does not feel like moving all around
     
  10. Kiddycrack

    Kiddycrack Silver Member

    Reputation Points:
    13
    Joined:
    Jan 10, 2010
    Messages:
    131
    SWIM said "Snorting ritalin could damage nasal passages and tissues but it also has a higher bioavailability compared to oral or sublingual, but everyones different." SWIM has since quit snorting ritalin due to being switched to Concerta. SWIY could also increase the bioavail from oral if SWIY takes an antacid about 10 or so mins before taking ritalin.
     
  11. dennis1999

    dennis1999 Newbie

    Reputation Points:
    -15
    Joined:
    Sep 4, 2011
    Messages:
    19
    i love it under the tongue take 4 pills after they disolved i do another 4
    after about a hour i get a very bad feeling like sort of panic attack
    and then it start very mellow
    feels soooo good very talkative
    never ever through my nose
     
  12. klaus1971

    klaus1971

    Age:
    45
    Reputation Points:
    -70
    Joined:
    Oct 8, 2011
    Messages:
    26
    improve your sublingual by first rinsing your mouth
    something with menthol in it
    it will improve the absorbation of the crushed ritalin
    menthol dilates the blood vessels

    klaus1971 added 1174 Minutes and 41 Seconds later...

    found out that just have to rinse your mouth with that dental water as long as its contains alcohol and menthol

    klaus1971 added 686 Minutes and 41 Seconds later...

    i cant for some reason dont put links here put
    google for

    Buccal Mucosa As A Route For Systemic Drug Delivery: A Review

    go down to list to super improve your subligual ritalin
     
    Last edited: Oct 14, 2011
  13. EscapeDummy

    EscapeDummy Palladium Member

    Reputation Points:
    2,716
    Joined:
    Apr 15, 2009
    Messages:
    1,799
    As you allude to, sublingual administration bypasses first pass metabolism. You say different routes of administration shouldn't change the types of effects, just the intensity/severity. However, this is not true. Not only does the concentration of the drug in the bloodstream matter, but so does the rate of absorption - how fast the concentration changes with time. I'm sure there have been pharmacokinetic/dynamic studies which investigate how concentration, rate of change of concentration, and the 2nd derivative with respect to time (the acceleration of the concentration) change effects.

    As an example, eating and smoking marijuana produces markedly different effects. Ketamine is a prime example of a substance where effects are VASTLY different depending on the route of administration chosen. Same goes for MDMA (insufflated anecdotally tends to be more speedy, while oral more empathogenic/euphoric), salvia (sublingual salvia is nothing like the intensity of smoked salvia), I'm sure there are others.

    The dummy also has experienced sublingual (adderall) to last longer and smoother, without as much ups and downs, as oral. He would guess it is because oral adminstration causes a sudden spike in amphetamine bloodstream concentration, while sublingual causes a more steady, smooth change.
     
  14. meth_latex_catsuit_doll

    meth_latex_catsuit_doll Silver Member

    Reputation Points:
    15
    Joined:
    Jul 24, 2011
    Messages:
    83
    SWIM will only put a Ritalin tablet under the tongue when plugging or snorting is impractical. (ie, in-line skating the public trails).

    Having also a pierced tongue, adds to the absorption efficiency. Downside is that huge amount of plaque accumulates both on jewelry and teeth which accelerates tooth decay.

    SWIM believes that the risk of tooth decay is not worth it for regularly administering Ritalin sublingually. Only occassionally if needed, and brush teeth as soon as possible.
     
  15. klaus1971

    klaus1971

    Age:
    45
    Reputation Points:
    -70
    Joined:
    Oct 8, 2011
    Messages:
    26
    better put it at your cheeks
    and some are worried for teeth decay taking a pill subligual
    but they take tons of candy, cola and all that shit in their mouth
    but don't take rit under your tongue that's baaaaaaaaaaaaad
     
  16. meth_latex_catsuit_doll

    meth_latex_catsuit_doll Silver Member

    Reputation Points:
    15
    Joined:
    Jul 24, 2011
    Messages:
    83
    Dipping Ritalin between the lower cheek and lower gum or lip has a bioavailability of around 70%, still short of 95% BA by plugging it rectally.


    Also, licking candies don't become anywhere as acidic as when ritalin powder comes in contact with saliva. Rubbing Ritalin promotes ulceration of gums and the underlying bone. Mixed with saliva creates an extremely acidic solution which erodes tooth enamel and exposes the underlying dentine to decay-causing bacteria.

    Bad idea.

    SWIM still favours plugging Ritalin. Just plugged a 50mg solution -- Extremely efficient, clean, fast and very safe.
     
  17. usually0

    usually0 Silver Member

    Reputation Points:
    280
    Joined:
    Jan 11, 2012
    Messages:
    379
    Can you quote any sources for these claims? These claims point to undesirable negative health side effects, so one should be sure they're right before claiming something like this.
     
  18. meth_latex_catsuit_doll

    meth_latex_catsuit_doll Silver Member

    Reputation Points:
    15
    Joined:
    Jul 24, 2011
    Messages:
    83
    "Meth mouth" a known oral disease known to be caused by caused by speed such as amphetamines (Dexedrine, Adderall), cocaine and methylphenidate (Ritalin).

    A good starting point, specifically discussing Meth mouth and Stimulants is Wikipedia. Type "Meth Mouth".

    Sub-lingual and Dipping stimulants in the Gums IS a health hazard, and isn't worth of being listed as an acceptable ROA. It's reckless and plain foolish considering other, more efficient ROA.

    In addition to the irreversible tooth and gum damage, the fillers contained in meds not designed to be administered sub-lingually, clog the coronary artery, causing a buildup of cholesterol and dramatically increasing the risk of a heart attack.

    The human body is the greatest instrument we have and we shouldn't be reckless. It's ok to have fun once in a while, live long and enjoy life for a very long time!

    10 minutes ago SWIM finished plugging 40mg Ritalin... procedure took 5 minutes in all... quick, easy, efficient. Just kicked fast and hard into full force and feeling a very intense adrenaline rush -- without the nasty taste or risks associated with railing and/or sub-lingual.
     
  19. usually0

    usually0 Silver Member

    Reputation Points:
    280
    Joined:
    Jan 11, 2012
    Messages:
    379
    Thanks for expanding on what you meant. There's what wikipedia had to say about "meth mouth". Pretty interesting, thanks for pointing this out.

    While it noted that "meth mouth" can be caused by methylphenidate use, I didn't see anywhere that sublingual ROA of methylphenidate causes "meth mouth".

    Rather, it said that "meth mouth" is "probaly caused by by a combination of drug-induced psychological and physiological changes resulting in xerostomia (dry mouth), extended periods of poor oral hygiene, increased consumption of sugared soft drinks, and teeth clenching and grinding (bruxism)."

    Of course, this only a wikipedia article, there is much better sources out there. But, it would seem from wikipedia that sublingual ROA of methylphenidate wouldn't cause "meth mouth" more than any other ROA of methylphenidate.

    However, the Pennsylvania Dental Association maintains that "the acidic ingredients of methamphetamine can damage teeth." This might suggest that methylphenidate's ingredients are also acidic. But it leaves out, what ingredients are acidic, and the acidity of methylphenidate's ingredients.

    I'm looked into the source from Pennsylvania Dental Association and dug a little deeper. And here's an excert:

    http://www.padental.org/AM/Template.cfm?Section=Media&Template=/CM/HTMLDisplay.cfm&ContentID=16105

    Any of those ingredients are definitly not present in methylphenidate, so I would say that Methylphenidate isn't acidic like they claim illicit methampetamines are. Although I wonder if these ingredients would even be in illicit Methamphetamines, I'm not sure really.
     
    Last edited: Apr 27, 2012
  20. alorin13

    alorin13 Newbie

    Reputation Points:
    0
    Joined:
    Mar 14, 2014
    Messages:
    1
    I a have closet monster who has been recently looking to get more euphoria from Ritalin and stumbled across numerous posts where SWIY mentioned that sublingual metylphenidate has same effects as intranasal. so the monster decided to try the method. Monster has medikinet 10mg instant release. he sucked thenm under the tongue, did not make a 'salive pool' , from previous experienced with benzos, it took 5 minutes for the tablet to dissolve. 10 mg - no effect, another 20 in a while still not described euphoria, only slight agitation, no rush. he decided to try one more 10ng - no pronounced effect. the remaining him magically turned into decent powder and snorted through his monster nostrils. he felt euphoric, he felt great and havin some zopiclone did not have much crash after. monster claims that for him rit sub lingual is useless. if monster wants to work - orally, whats to have a good time- snorting. (scared as shit of needless, plugging kinda repels me. so take this in consideration if you have tried 10 - 15 mg sub ling and the are no pronounced desired effects, stop and take out your old razor/ credit card/ cyclindric deodorant... well you all know what to do