Suboxone equal to how many mg's of Morphine?

Discussion in 'Buprenorphine' started by Wyborowa, Aug 21, 2006.

  1. Wyborowa

    Wyborowa Silver Member

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  2. Fantasian

    Fantasian Gold Member

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    this depends, is SWIF using for Pain killing or recreation.

    It is important to note that the morphine will be significantly more recreational even at the same equivelant dose as it has no antagonist properties. Suboxone is a mix of Nalaxone and Buprenorphine if i remember correctly. (4 to 1 to be exact)

    Buprenorphine normal theraputic dose is 8mg and Morphine is 10mg, it is widely accepted that not much tolerance develops from Buprenorphine. You should try a 15mg morphine dose and work up assuming he is using orally.

    Important Note: DO NOT MIX THE TWO! The antagonistic effects of Buprenorphine will negate the morphine or other non synthetic opiates.

    As for comparison to other opiates google an opiate comparison table.
     
    1. 3/5,
      The thereputic range is <1mg - 32mg. The theraputic dose is not 8mg
      Jan 13, 2015
    2. 4/5,
      Great harm reduction to mention the antagonist effects of buprenorphine.
      Nov 18, 2010
  3. Wyborowa

    Wyborowa Silver Member

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    yes, this is for swims recreation....and I couldn't find a comparison table, is there one posted....

    like how many mg's of hydrocodeine is equal to "X" mg's of morphine Sulfate (MS Contin)
     
  4. Forthesevenlakes

    Forthesevenlakes Platinum Member

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    google "opiate converstion table". however, the ones I has found do not have buprenorphine (suboxone) in them. maybe one exists with it in there, I am too tired to look at the moment but will check it out later.

    heres a table to help with the hydrocodeine/morphine conversion though.
     
  5. Wyborowa

    Wyborowa Silver Member

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  6. Micklemouse

    Micklemouse Platinum Member & Advisor

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    This cannot be stressed enough! In addition to negating the effects of morphine, it may forcibly rip any other opiates in your system out of your system, bringing on intense withdrawals very quickly. Be careful.

    Indiedrugmusic - please use the search engine, & if SWiY don't find the answer to your question there start a new thread or ask in a thread relating to poppy seed tea. That question has nowt to do with the question being asked in this thread!
     
    Last edited: Aug 23, 2006
  7. lexifer

    lexifer Titanium Member

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    im pretty sure i read on erowid somewhere that 10 milligrams of morphine is equivalent in potency to 600 micrograms buprenorphine. so that would mean an 8mg suboxone would have the potency of about 133mg of morphine. im almost positive that the equivalency is indeed 600mcg bupe to 10mg morph.
     
  8. dude

    dude Newbie

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    Ok I had a question for an experienced Opiate / Suboxone user. And first off, for the tough guys out there, please don't tell swim to search for the answer himself because it's out there somewhere. I did a bunch of reading and can't get a good solid answer nor directions for what I want to do. Swim's friend is sniffing around 10to15 30mg Roxi's / day and wants to lower his tolerence back down to a few a day and also wants to get high like he used to. I got a hold of 10 8mg Suboxone's and would really appreciate the proper way to use these to lower his tolerence. Swim's head is spinning from everyone's opinion on what the Nalaxone will do and what it is for and what swallowing vrs subligually will do and some say wait 2 weeks before hitting the Oxy's again and some say to wait 3 days and so on and so on. Will some nice experianced brother swim help swim's friend out here so he does it right and doesn't waste the Suboxones and/or hurt himself? Thanks in advance!
     
  9. Fantasian

    Fantasian Gold Member

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    If in the USA suboxone is the same as the UK do not swallow, it's completely ineffective via this route. As to dosing down its very person specific and difficult to accertain for any of us here on the forum. It's like asking a blind man which dress looks better on a lady, even if described it's still very easy to be wrong. in an attempt to do so all the same what is you's weight, age and gender.
     
  10. dude

    dude Newbie

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    Well I took an 8mg sub and it was a horrible nitemare. Swim will start another post in the proper place and explain what happened for those who would benefit from it.
     
  11. sarbanes

    sarbanes Newbie

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    Buprenorphine's agonist potential is 75 x morphine*. Therefore (depending on other variables as well), 8mg buprenorphine is equivalent to 600mg morphine w/w. Do a little reverse algebra to figure out the inverse. Buprenorphine’s agonist (profile), has it lasting twice as long as morphine. Buprenorphine is also a strong antagonist, being 4 X nalorphine w/w*.
    *J. W. Lewis, Adv. Biochem. Psychopharmacol. 8, 123 (1974)
     
  12. JaWill88

    JaWill88 Titanium Member

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    swilexifer yes this is correct. swims dose of buprenorphine is 32mg and that would technically be equivelant to like 500 mg of morphine. but of course it really isnt like taking 500mg of morphine.
     
  13. JaWill88

    JaWill88 Titanium Member

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    if swiys friend wants to lower tolerance and get high again... then abstain from opiate for a few weeks will do the trick. if friend has physical habit (which appears so) then friend should quit using the current opiods, BE IN WITHDRAWAL so wait about 24 - 48 hrs after last use, and take an 8 mg suboxone. this will cure the withdrawals. You has to feel some withdrawal though before taking it. then You should use it (one a day) for about 7 days for detoxing. staying on it any longer will probably cause a physical dependance to the suboxone which really is worse than even heroin withdrawals especially cause they last so damn long. also if You isnt in withdrawal then there are still significant amounts of opiates in the receptors and the buprenoprhine (suboxone) will kick it out and You will go into withdrawal. the nalaxone has nothing to do with that dont listen to anyone who says it dose. the only reason nalaxone is in there is to prevent people from shooting it. oh yeah and it must be taken under the tongue so the buprenorphine will work and the naloxone wont.
     
  14. SomniphileXII

    SomniphileXII Silver Member

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    I just started 8mg daily suboxone today. I was taking doses of 50mg morphine IV at a time if it was around, and PO 500mg-700mg codeine every day for quite a while. The ceiling doses of codeine ended up doing very little but kill a bit of pain and negate the sickness, so obviously IVing morphine was the way to get a solid nod.
    All together I was taking an average of 120mg of morphine a day this year. (Codeine metabolizes to 10% morphine)
    Before that I was taking more like 40mg morphine. And remember that my averages here are with an assumed 70-100% bioavailability, never eat morphine, like.

    So last week I started on 10mg methadone a day and that was a significant jump down from my usual dose, and after two or three days it started to take the edge off the sick.
    I waited 48 hours to score 16 on the COWS and ate 4mg buprenorphine half an hour ago.

    At this point my sickness has subsided significantly and probably feels like a 40mg or so of morphine. Minus the joy of course since morphine makes me cum and suboxone obviously doesn't.

    Because of the long half life, I can't say its quite as potent in effect as it actually is. I'm under the impression now that buprenorphine is more potent than diamorphine, or at least comparable.

    Here's a good analogy like:
    The potency of alprazolam is 0.5mg to 10mg diazepam. Now, clonazepam is the same potency as alprazolam (0.5mg), but the half life of clonazepam is at average 30 or 40 hours. The half life of alprazolam is around 10 hours.
    Because of this, 0.5mg of alprazolam is going to have a stronger effect than 0.5mg clonazepam.

    Same idea with buprenorphine, more time = less effect.

    Don't use that as justification for doubling up on doses though! The medicine is still as potent, it just feels lesser.

    Just my input. Seriously though, bupe is more potent than scag innit?