1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.

Syrian Rue contadictions

Discussion in 'Ethnobotanicals' started by Potter, May 24, 2006.

  1. Potter

    Potter Platinum Member & Advisor

    Reputation Points:
    Apr 1, 2005
    from U.S.A.
    I am wondering how the list of foods that contrdict MAOI's should be applied to harmala? How long before consumption should these foods be avoided? how long after? Are there any that can enhance the experiance?
  2. rxbandit

    rxbandit Gold Member

    Reputation Points:
    May 19, 2006
    from U.S.A.
    • the list of contradictions are;

      Sedatives, tranquilizers, antihistamines, narcotics and alcohol) any of which can cause hypotensive crisis (severe blood pressure drop); and amphetamines (even diet pills), mescaline, asarone, nutmeg (active doses), macromerine, ephedrine, oils of dill, parsley or wild fennel, beer, wine, cocoa, aged cheese and other tyrosine containing foods (tyrosine is converted into tyramine by bacteria in the bowel) ) any of which can cause hypertensive crises (severe blood pressure rise).

      ALCOHOLIC BEVERAGES - avoid Chianti wine and vermouth. Consumption of red, white, and port WINE in quantities less than 120mL present little risk (Anon, 1989; Da Prada et al, 1988; McCabe, 1986).

      BEER and ALE should also be avoided (McCabe, 1986), however other investigators feel major domestic (US) brands of beer is safe in small quantities (1/2 cup or less than 120 mL)
      (Anon, 1989; Da Prada, 1988), but imported beer should not be consumed unless a specific brand is known to be safe.

      WHISKEY and LIQUEURS such as Drambuie(R) and Chartreuse(R) have caused reactions.

      NONALCOHOLIC BEVERAGES (alcohol- free beer and wines) may contain
      tyramine and should be avoided (Anon, 1989; Stockley, 1993).

      BANANA PEELS - a single case report implicates a BANANA as the-causative agent, which involved the consumption of whole stewed-green banana, including the peel. Ripe banana pulp contains 7-mcg/gram of tyramine compared to a peel which contains 65 mcg/gram-and 700 mcg of tyramine and dopamine, respectively (McCabe, 1986).
      BEAN CURD - fermented bean curd, fermented soya bean, soya bean-pastes contain a significant amount of tyramine (Anon, 1989).
      BROAD (FAVA) BEAN PODS - these beans contain dopa, not tyramine,-which is metabolized to dopamine and may cause a pressor reaction-and therefore should not be eaten particularly if overripe-(McCabe, 1986; Anon, 1989; Brown & Bryant, 1988).
      CHEESE - tyramine content cannot be predicted based on appearance,-flavor, or variety and therefore should be avoided.
      CREAM CHEESE and COTTAGE CHEESE have no detectable level of tyramine (McCabe,-1986; Anon, 1989, Brown & Bryant, 1988).
      FISH - fresh fish (Anon, 1989; McCabe, 1986) and vacuum- packed-pickled fish or CAVIAR contain only small amounts of tyramine and-are safe if consumed promptly or refrigerated for short periods;-longer storage may be dangerous (Anon, 1989). Smoked, fermented,-pickled (Herring) and otherwise aged fish, meat, or any spoiled-food may contain high levels of tyramine and should be avoided-(Anon, 1989; Brown & Bryant, 1988).
      GINSENG - some preparations have resulted in a headache,-tremulousness, and manic-like symptoms (Anon, 1989).
      PROTEIN EXTRACTS - three brands of meat extract contained 95, 206,-and 304 mcg/gram of tyramine and therefore meat extracts should be-avoided (McCabe, 1986). Avoid liquid and powdered PROTEIN DIETARY-SUPPLEMENTS (Anon, 1989).
      MEAT, nonfresh or liver - no detectable levels identified in fresh-chicken livers; high tyramine content found in spoiled or unfresh-livers (McCabe, 1986). Fresh meat is safe, caution suggested in-restaurants (Anon, 1989; Da Prada et al, 1988).
      SAUSAGE, BOLOGNA, PEPPERONI and SALAMI contain large amounts of-tyramine (Anon, 1989; Da Prada et al, 1988; McCabe, 1986). No-detectable tyramine levels were identified in country CURED HAM-(McCabe, 1986).
      SAUERKRAUT - tyramine content has varied from 20 to 95 mcg/gram-and should be avoided (McCabe, 1986).
      SHRIMP PASTE - contain a large amount of tyramine (Anon, 1989).
      SOUPS - should be avoided as protein extracts may be present; miso-soup is prepared from fermented bean curd and contain tyramine in-large amounts and should not be consumed (Anon, 1989).
      YEAST, Brewer's or extracts - yeast extracts (Marmite) which are-spread on bread or mixed with water, Brewer's yeast, or yeast-vitamin supplements should not be consumed. Yeast used in baking-is safe (Anon, 1989; Da Prada et al, 1988; McCabe, 1986).--The foods to use with caution list categorizes foods that have been reported-to cause a hypertensive crisis if foods were consumed in large quantities,-stored for prolong periods, or if contamination occurred. Small servings-(1/2 cup, or less than 120 mL) of the following foods are not expected to-pose a risk for patients on MAOI therapy (McCabe, 1986).
    Foods To Use With Caution:-
    • (1/2 cup or less than 120 mL)--Alcoholic beverages - see under foods to avoid.
      AVOCADOS - contain tyramine, particularly overripe (Anon, 1989)-but may be used in small amounts if not overripened (McCabe,-1986).
      CAFFEINE - contains a weak pressor agent, large amounts may cause-a reaction (Anon, 1989).
      CHOCOLATE - is safe to ingest for most patients, unless consumed-in large amounts (Anon, 1989; McCabe, 1986).
      DAIRY PRODUCTS - CREAM, SOUR CREAM, cottage cheese, cream cheese,-YOGURT, or MILK should pose little risk unless prolonged storage-or lack of sanitation standards exists (Anon, 1989; McCabe, 1986).
      Products should not be used if close to the expiration date-(McCabe, 1986).
      NUTS - large quantities of PEANUTS were implicated in a-hypertensive reaction and headache. COCONUTS and BRAZIL NUTS have-also been implicated, however no analysis of the tyramine content-was performed (McCabe, 1986).
      RASPBERRIES - contain tyramine and small amounts are expected to-be safe (McCabe, 1986).
      SOY SAUCE - has been reported to contain large amounts of tyramine-and reactions have been reported with teriyaki (Anon, 1989),-however analysis of soy sauce reveals a tyramine level of 1.76-mcg/mL and fermented meat may have contributed to the previously-reported reactions (McCabe, 1986).
      SPINACH, New Zealand prickly or hot weather - large amounts have-resulted in a reaction (Anon, 1989; McCabe, 1986).
      More than 200 foods contain tyramine in small quantities and have been-implicated in reactions with MAOI therapy, however the majority of the-previous reactions were due to the consumption of spoiled food. Evidence-does not support the restriction of the following foods listed if the food-is fresh (McCabe, 1986).

      my rule is usually 24 hours before and after but most of these foods will just give you some nasty side effects like purging and raised heart rate but no serious implications if your diet is just a little off.

      any of the atropa alkaloids(atropine, scopalamine, hyscocine) will potentiate the experience greatly but very small doses are all that is needed. also any tryptamine is greatly potentiated by the harmala alkaloids so shrooms and DMT are alot more potent and with this combination many report telepathy and feeling of time travel which SWIM can attest too.

      harmaline will make you feel like your about to trip but its neccesary to combine it with something to push you over.