Effects - would having taken MDMA recently diminish the effects of cocaine ?

Discussion in 'Cocaine & Crack' started by ElectroNicaPO1, Feb 14, 2005.

  1. ElectroNicaPO1

    ElectroNicaPO1 Newbie

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    Do you think that if someone experiences MDMA before ever trying cocaine that person will not feel the cocaine as much?
     
    Last edited by a moderator: Sep 22, 2007
  2. bman1

    bman1 Palladium Member

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    People feel cocaine mainly from dopamine and norepinephrine


    people feel MDMAmainlyfrom serotonin


    They work off different neuroltransmitters so should not have an effect on each other if not taken together
     
  3. ElectroNicaPO1

    ElectroNicaPO1 Newbie

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    Thanks.. [​IMG]
    Just curious as I am in this situation.
     
  4. dj_c

    dj_c Newbie

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    I started doing cocaine before touching XTC and SWIM still likes both but says if there was no comedown associated with taking street xtc he would be doing it all the time. He however still enjoys getting very messy on the powder!
     
  5. bowlingforcindy

    bowlingforcindy Newbie

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    i first started on XTC. then after about 4 pills on a night out, i had my firs line of coke. it was shite. the night was shite, the pills wernt working and then i had my first line in the toilets. the only thing that i felt was the pills starting to work. coke just doesnt work for me. my sister has done it and she sais it doesnt make her feel any different at all. i did a gram in one go once and that worked. fucked me up for hours. i prefer just puttin it on my gums and it feels funny
     
  6. dolphinsnow18

    dolphinsnow18 Newbie

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    I thoughtseratonin levels suppressed dopamine? Wouldnt you thenloseany euphoria related to dopamine in that case?
     
  7. Lacognac69

    Lacognac69 Silver Member

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    I believe that i've heard that ecstasy also does stimulate dopamine release or keeps dopamine around longer in the synapse of the nerve cell along with its effects on serotonin. I'm not sure if im totally correct with the dopamine thing, but I remember hearing it somewhere. As far as taking E before taking coke, i think the ecstasy would just make coke a lot more boring, unless you did a lot of coke. Coke is definitely a nice thing to have around to fuck around with though.
     
  8. bman1

    bman1 Palladium Member

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    I has heard this also that is why I said mainly. Swim also thinks the question was not taken together but one before the other at seperate times. wich should not matter a person might not like it as much but but effects should be the same
     
  9. Hyperreal

    Hyperreal Gold Member

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  10. lamborghini1107

    lamborghini1107 Newbie

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    Wouldnt coke plus ecstasy be dangerous?

    I never mix anything.....never....too risky
     
  11. Hyperreal

    Hyperreal Gold Member

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    Mixing coke and ecstasy isn't dangerous, as long as your heart is healthy.


    It's a misconception that mixing drugs is dangerous, unless there's a specific reason that a combination would be dangerous (serotonin syndrome, cardiac over-stimulation, metabolites). If you never mix drugs because you think it's dangerous, you're missing out on a kaleidoscope of experiences, based on a false assumption. You just need to do your research and know what combinations are safe and what combinations aren't
     
  12. lamborghini1107

    lamborghini1107 Newbie

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    eh people have died from mixing
    drugs....coke+alcohol= death sometimes

    Its generally not good to mix stimulants with
    depressants......so how can you say its completely
    safe?
     
  13. lamborghini1107

    lamborghini1107 Newbie

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    oh sorry i didnt finish reading youre entire post...you
    did say that some things arent safe.....im really
    jacked right now....lol you know how that iss..

    ive been at it since about 2 in the morning.....and still
    got a half gram left :)
     
  14. TranceAddict

    TranceAddict Silver Member

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    your right about that. mixing can be no good sometimes. I remember a
    few months ago I was at a getty with some friends and well everyone was
    pretty much doing drugs. One of my friends was doing coke, drinking,
    and smoking. When we all came inside after smoking we were just in
    there chillin and out of no where my friend gets up and slowly,
    completely disoriented, walks to the bathroom. she was there for 3
    minutes so we go and check on her and she was completely unconscious
    with a real bad headache. looks like that coke/alcohol mix got to her
    real bad. She was so confused when she got up and we freaked out a bit
    because her heart was not doing good either.
     
  15. shneddi

    shneddi Newbie

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    yeh doing coke on e kinda brings you down off the E but it effects you in a different way. it makes me really sharp and concentrated.
     
  16. Dr. Gonzo

    Dr. Gonzo Newbie

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    wtf? I like to mix everything the more substances the better :)
     
  17. Alfa

    Alfa Productive Insomniac Staff Member Administrator

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    So, you'll be crashing head first now and then? Or have you been so lucky that you did not experience that yet?
     
  18. invictvs

    invictvs Newbie

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    If you read hyperreal's post he/she says you need to do your research, (i.e. drug interactions). Coke taken with alcohol forms "cocaethylene", a metabolite which is more toxic than coke taken aloneand last longer in the body.


    I don't know of any negative druginteractions with Coke and MDMA... but from practical experience it's better to do coke before MDMA because coke zaps swim out of an MDMA buzz, but not vice versa.


    Maybe there should be a coke interaction sticky?
     
  19. sine~language

    sine~language Newbie

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    I just think the common denominator with a lot of dangerous and fatal
    drug mixes is Alcohol. When I drink, I only drink. Had too many
    problems with taking other drugs whilst the wobbly boots are on.
     
  20. IvoryQueen

    IvoryQueen Silver Member

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    I agrees wit that, if u do the coke then take the pill straight after, as the coke starts to wear off the mdma kicks in. Thats how SWIM always does it andd she has no complaints [​IMG]





    enjoy x