Article Discussion for Dopamine

Comments

  1. calliope

    calliope Fictional Member Gold Member Sponsor

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    from a nutshell, an infinite space
    Hi methylman, Good start on the article, hopefully my posting this comment will allow you to make a reply so whatever the glitch is is resolved and you can leave a discussion post.
    calli
     
  2. methylman251

    methylman251 Titanium Member

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    I'm going to hope so, Thanks for that Calli!!

    Ok basically I've started off with the dopamine wiki, I've added all the headings I think are necessary at the moment and over the next couple of days will fill them all then add references check the grammar and it'll be done. This and the serotonin one can then serve as a template (which sections need to be expanded upon etc, other links and information that might be important) so we can go ahead and look at doing the rest of the neurotransmitters
     
  3. tomkat

    tomkat Silver Member

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    Just wanted to let you know how great the dopamine article is looking. It's easy to read, yet detailed at the same time. I like how you inserted definitions of potentially difficult to understand terminology within the text. For example I loved what you did below...

    "The rate-limiting enzyme (the enzyme which makes the least of the molecules along the biosynthetic pathway) is Tyrosine Hydroxylase (TH)."

    ^
    Providing the definition along side the word makes it easier on ADHD individuals (such as myself), who have a general understanding of neurotransmiters, but do not have the motivation/patience to look up every unknown word or definition.

    The balance of information is great as well. Whenever I set out to learn more about complicated subjects (such as neurotransmiters) the text is often overly complicated and too in depth or so shallow that I do not learn anything new. Your article is perfectly suited to be used as a foundation to build further information upon (if that makes sense to anyone, lol.)

    Keep up the good work!
     
  4. methylman251

    methylman251 Titanium Member

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    Thanks!! Be sure to let me know if there i anything I haven't explained in enough detail.

    Just finished all but the interesting bits - the actual receptors themselves and function of dopamine.

    methylman251 added 1360 Minutes and 21 Seconds later...

    Well the function of dopamine receptors evidently turned out to be far more complex (believe it or not) than I thought. But I've pretty much done the drugs acting on dopamine receptors, dopamine and addiction bits and the stimulants and dopamine induced neurotoxicity. Then it'll just take an edit to make sure its all explained in simple terms and well defined etc... and it should be a pretty comprehensive review of dopamine (and all the drug dopamine interactions but I'll put it at the end).
     
  5. sprinkles

    sprinkles Silver Member

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    Great work so far! I think it would also be interesting to include a section on how dopamine and the reward pathways are also activated/involved in intimate relationships, that is thier role in affection, attachment etc.. Just an idea.
     
  6. docta

    docta Idiot Savant Gold Member Donating Member

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    The Dopamine degradation image, it seemed a bit undefined and fizzy.

    What do we think about changing it out for this one?

    I dropped the aldehyde intermediates as there not relevant to the trans from DA to HVA


    [IMG]http://www.drugs-forum.com/forum/attachment.php?attachmentid=30638&stc=1&d=1356744086[/IMG]
     
  7. methylman251

    methylman251 Titanium Member

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    Yeah that looks good, we should swap them over
     
  8. Wanderer

    Wanderer Platinum Member & Advisor

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    This is a great start for a complete Wiki section on neurotransmitters.

    Once we have the article honed further, we should create a template for the template library.

    Also, there should probably be a category for neurotransmitters which can collect and index the neurotransmitters.

    Be well...
     
  9. methylman251

    methylman251 Titanium Member

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    I don't have much to go, just doing it in between uni/over the weekend (should be done this weekend). I'll put up what I think a good outline would be for neurotransmitters in general in the wiki discussion (with a few headings from dopamine changed to be more generalised to suit the other neurotransmitters) soon to see if others have feedback about anything missing.

    I agree it would be good to have a nice neurotransmitters index, its useful information and generally hard to come by something laid out like this (wikipedia is pretty crap... way too detailed/poorly defined/outdated info) particularly for those who just want to have a brief read.

    Also don't worry I haven't completely forgotten about this and left it without references etc, I've just run into a few really busy weeks but once that's out of the way I'll get back to finishing it. Its actually frustrating cos the bits left to go are the best sections and it'll be pretty cool to learn about, I just need to get all this crap out of the way first.
     
  10. methylman251

    methylman251 Titanium Member

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    That may have taken far far longer than I thought but thats now pretty much done. Several sections could have more detail but going into specifics would be better off going into different sections e.g addiction. I've tried to put in brackets with definitions where I could so people who don't have a medical sciences background could still read it and learn a few things too.

    I hope thats an ok starting point for a neurotransmitters section and at some point soon I'll paste a template into the drug wiki group discussion about it with a brief explanation of what I think should be under each section so people can add to it or expand the template so all the info we need is there.