Salvia divinorum

Introduction

Salvia Divinorum, also called Diviner's Sage, Sage of the Seers, Sally-D, Ska Pastora, and magic mint is a psychoactive plant in the Lamiaceae family (mint). The plant's use as a spiritual healer has been an everlasting tradition to the Mazatec shamans in Oaxaca, Mexico, where the plant grows natively. Today, salvia is being used around the world for its spiritual and hallucinogenic effects. Salvia Divinorum’s intense and short effects are gaining popularity. The plant has been banned in several countries, yet overall most countries have barely heard about the plant. Due to its rise in popularity, it is receiving legal attention. However, few studies have been done on salvia to conclude its negative consequences or medical uses. Studies have so far mostly been made by private researchers and a few universities. The DEA has also recently begun conducting research to determine its legality in the United States.

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Effects of Salvia Divinorum

While some people would classify salvia divinorum as a dissociative and others would say it’s more of a psychedelic, most people can agree that the salvia divinorum experience is completely unique. Physically, one can get elevated blood pressure, sweatiness, uncontrollable laughter, heavy breathing, somnambulant behavior, and the feeling of immense gravity. However, what represents the physical experience of salvia divinorum can completely contradict the mental state. The onset is pretty quick, usually about 1 minute, and after that for a period of one to eight minutes one can experience out of body/near death experiences, form into an object, visit other dimensions, meet divine entities, see vivid colors or geometric patters, hear voices, and achieve flashbacks. After the intense part of the experience subsides, one feels an “afterglow” from salvia. As salvia wears off there is a feeling of a slight body high, possibly some confusion or disorientation, and elevated mood. If salvia is ingested sublingually, the effects are much mellower, but can last up to an hour rather than less than thirty minutes.

A web-based survey of 500 people noted the following effects:

feelings of increased insight (47%)
improved mood (44.8%)
calmness (42.2%)
increased sense of connection with the universe or nature (39.8%)
weird thoughts (36.4%)
things seem unreal (32.4%)
floating feeling (32%)
increased sweating (28.2%)
body felt warm or hot (25.2%)
reported persisting ( 24 hr) positive effects (usually an increased sense of
well-being) on at least 1 occasion, 25.8%.
4.4% had persisting negative effects (most often anxiety). [1]

Using Salvia Divinorum

This section will go over all there is to know about using Salvia divinorum.

Dosage

One of the things that's unique about Salvia divinorum is its complete randomness when it comes to dosage for different people. The most experienced drug user could have a wild experience on only leaves while a person new to drugs might need a powerful extract just to get a feeling. However, whether one has a natural tolerance or not, is always best to start with salvia divinorum's weakest dose to make sure one doesn't get blown away on a terrifying experience. People usually start by smoking leaves. The dosages go as follows:

Smoked Salvia divinorum Leaf Dosages (Avg: 2.5mg salvinorin A per g)


Light: .25g
Common: .5g
Strong: .75-1.00g

Onset : 30-180 seconds
Duration : 5-30 minutes
Normal After Effects : 30-60 minutes

Onset : 30-180 seconds
Duration : 5-30 minutes
Normal After Effects : 30-60 minutes


This is a summary of the basic time schedule and experience strengths for plain leaf. If one would want to calculate how much of the active chemical salvinorin A was going into his/her system, he/she would just calculate based on the salvinorin A leaf average (2.5mg per gram). This can be very useful if wanting to use a higher power extract.

Combinations with Salvia divinorum

Huge list of combos, needs expansion.

Ways of using Salvia divinorum

Smoking the plant material is by far the most common way of ingesting salvia. The best method (if possible) is to take a small pipe and inhale all of the hot smoke fast. The smoke must then be held in for at least 20 seconds before effects begin or taking another hit. Many people find that this smoking method is quite painful and induces coughing with substances like leaves and not so high extracts. A more common way (and sometimes more effective) is to use a water bong. The water in a water pipe cools the smoke allowing the user to take larger, deeper hits of the smoke. If more smoke can be inhaled into the lungs compared to smoke lost from hot inhalations, it's a fair trade-off. Note: There is a heated debate about the type of lighter to use when smoking salvia. Many people report better experiences using a butane torch lighter because it ignites the plant material much quicker and hotter. A torch lighter can be useful for igniting a lot of leaves quickly, allowing a lot of smoke to be produced. This also comes in handy when using a bong, that way more smoke can get through at once. When it comes to medium extracts, a normal lighter will work just as fine. The only thing that matters is that all of the material is burned and all the smoke is inhaled. A torch can also be more useful for high extracts with small doses. This is because the torch lighter can concentrate its flame at any angle so less accidents (such as blowing away the extract) are prone to happen.


There are also means of sublingual ingestion. A person can take fresh leaf (a quid) or a tincture preparation and hold it under his/her tongue. In order for the salvinorins to make it into the bloodstream, people have to hold the preparations under their tongues for at least 20 minutes. This method is healthier in that one doesn't have to smoke. But this is usually less preferred due to the weaker effects and disgusting taste of the preparations held in the mouth.

Uses of Salvia Divinorum

This section will cover the main reasons for Salvia divinorum use.

Recreational

Although salvia divinorum is not that popular at the moment, a large population of young adults have started using salvia for recreational purposes. Many people are drawn to its very intense psychedelic/dissociative experience caused by salvinorin A: a kappa opioid receptor agonist. Since the effects last less than an hour mostly and the intense effects last minutes, it makes it very possible to dose several times a day (not recommended). Many users feel comfortable using salvia because it's non-habit-forming. Salvia also does not form an apparent tolerance; the experience is usually of the same strength every time. However, some people report that after using salvia for a long time, its “magic” starts to disappear. In fact, a handful of people even report a reverse-tolerance. One of the things about salvia however is that a person can be naturally tolerant to salvia without having used it once, which can be very frustrating in that that person would have to use very strong extracts to achieve certain effects.

Medicinal


The Mazatec Indians of Mexico used salvia divinorum in low doses for illnesses such as diarrhea, anemia, headaches and rheumatism. Today, little research has been made upon salvia's medicinal uses and so far it has not been approved for it. However, studies in psychological institutions are showing that salvia may have anti-depressant effects. PhD Karl R. Hanes reports about a “26 year old woman with treatment-resistant chronic depression who reports long lasting alleviation of symptoms with acute and chronic administration of Salvia divinorum”. Studies are also showing that neoclerodane diterpenes like salvia have medicinal potential for treating withdrawal symptoms of amphetamines and opiates. These however are still only theories and have not been legally approved as medicinal uses.

Spiritual

There are many users that claim to experience very spiritual trips such as meeting entities or seeing alternate supernatural realities. Certain people have taken salvia use as a form of spiritual introspection. In the plant's origin of Oaxaca, Mexico, the Mazatec shamans used to induce visions for spiritual healing. It was also used as medicine to the semi-magical disease panzon de borrego, or “swollen belly.” Certain regions of the world still continue its use as a spiritual guide and eye-opener to alternate realities.

Popularity of Salvia Divinorum

salvia+divinorum


The dangers of Salvia Divinorum

At the moment, regarding research and experimentation throughout users, the only dangers identified are due to judgement. However, because of the nature of Salvia divinorum, most of the time even misjudgement will be forgiven.

Guidelines for safe use

One should have a safe experience if he/she follows these guidelines posted by forum member BA:
GUIDELINES FOR USING SALVIA INTELLIGENTLY AND SAFELY
Salvia divinorum is a remarkably safe herb, provided that it is used in a safe manner. It can produce fascinating experiences that are deeply enriching, provided that it is used intelligently. Please pay careful attention to the following basic safety guidelines:

  • NEVER USE SALVIA IF GUNS, KNIVES, OR OTHER DANGEROUS OBJECTS ARE WITHIN EASY REACH.
  • NEVER DRIVE WHEN TAKING SALVIA.
  • Choose the time and place of your salvia experience carefully. Privacy and safety are essential. Be very careful about heights, and open flames such as candles. Do not take Salvia when you may be interrupted by phone calls, visits, pets, children, etc. Turn off your telephone and set your answering machine to silently record incoming calls. You can return the calls in a couple of hours once you are sober.
  • Give careful thought to how much you will take, and how you take it.
  • After all smoking material is safely out, lie down in bed, on a couch, or on a carpet. You are much safer lying down than you would be stumbling around. Stay put for the rest of the experience. The visionary effects are best perceived with eyes closed.
  • Have a sitter (this is especially important if you are new to Salvia, taking a high dose, smoking a strong extract, or using a very strong delivery system (such as vaporization).
  • Volunteer to be a sitter for others.
  • If you have mental health problems, don't take Salvia without first discussing it with your therapist, or doctor.
  • Practice and encourage responsible use. don't give Salvia to minors, or to violent or unstable people. Don't share it with strangers. Know who you are giving it to and know why they want to use it.
  • Never take Salvia while at work or in public. Keep it private. It's not for concerts. It is not for raves. It's not for large noisy parties. Better to use it in a quiet safe private place in the company of a close friend.
  • Mixing Salvia with other drugs or large amounts of alcohol may cause out-of-control behavior, or terrifying experiences. While experienced Salvia users have experimented with combinations, these are not for Salvia beginners, and are certainly riskier than just using Salvia by itself. While there are no known toxic drug-drug interactions between Salvia and anything else, this has not been studied scientifically.
  • Be extra careful of flames (candles, lighters, fire, etc.) when using Salvia.
  • Be very careful about using vaporized extracts, vaporized leaves, or smoking high-potency extract-enhanced leaves. These require a sitter to be present. Chewing quid or smoking leaves is much less likely to produce out-of-control behavior than these are.
  • Never use pure salvinorin A unless the dose you are taking has been weighed with an ultra-accurate balance that can weigh out doses in micrograms, and you know exactly how much you can safely take. Even if you do meet these requirements, you still should have a sitter present.

Toxicity

Many researchers have found salvinorin A to be very non toxic for rodents [2]. There hasn't been one reported death under the influence of salvia. However, there are a few salvia related incidents such as a suicide in which the user frequently used salvia (citation about that brett guy). There was also a salvia related car accident where the user dosed while driving over a bridge (citation needed). Use common sense, do not drive under the influence of salvia (it causes total loss of control in high doses). The guidelines mentioned above area great way to ensure safety. (Citation needed..coming soon)

Contraindications, side effects, and addiction

Since there is still isn't much research done on salvia, there aren't many contraindications between salvinorin A and other drugs. Even though there is no evidence of problems, it's still probably not a good idea to take salvia with MAOIs and it's probably not a good idea to combine with drugs that cause out of control behavior (it can make a lot of situations worse). So far there aren't many long term side effects noted. If there are, they are usually just minor things like being able to dream more often or elevated mood. As for addiction, salvia is very non-habit-forming. Almost all users are able to stop use without side effects or hints of withdrawal. Although salvia is not really addictive, it is still not recommended to take salvia very often because it can be very psychologically draining.

Growing Salvia divinorum

Note: It is not worth spending time growing salvia divinorum if one wishes to make profit, produce high amounts of extracts, or support one's salvia divinorum use if he/she does not have a high sensitivity to salvia.

It is possible to grow salvia divinorum hydroponically. Growing rates are much higher and more consistents, insensitive to seasons and their varying enlightment if artificial light is used. This allows at least sustainable production for one's uses.

General Growing


Salvia Divinorum is a beautiful, easy to grow, plant that produces many leaves. Salvia Divinorum is a semi-tropical perennial: it will grow every year as long as it's not exposed to extreme cold. Growing salvia divinorum inside tends to have better results. One can grow salvia divinorum outside as long the weather stays warm and there is good soil. Salvia divinorum should typically stay out of weather under 4.5 degrees Celsius. The plant also has better results when grown from cuttings rather than seeds. A healthy plant can grow several meters high and sometimes produce nine inch leaves. However this only when in good conditions. Under proper lighting conditions, salvia divinorum will also produce flowers.

Taking care of the plant

The salvia divinorum plant is particularly easy to grow and take care of. The plant should be watered often to keep the soil moist (but not too moist); the water should be able to drain from the pot. Salvia divinorum will need fertilizer. A little bit of any commercial fertilizer once every six weeks. The plant is best grown when it is only exposed to sunlight a few hours a day. It can handle sunlight as long as the plant gets enough mist on its leaves and water in its soil. And lastly, keeping insects and other pests away is a must. If grown inside, this shouldn't be a problem. However if insects get on the plant, it is best to rinse them off as efficiently as possible without hurting the plant.


For more information regarding troubleshooting or anything else, refer to the Drugs Forum Salvia Divinorum Growing Thread:


http://www.drugs-forum.com/threads/11365

Pictures coming soon!

Producing Salvia divininorum extract

There is typically only one simple method of obtaining extract with mild variations. They all have the same concept: the leaves are usually bathed in a solvent to extract the salvinorins. The solvent is then evaporated and the resulting crude extract is washed until clean. The final product is then measured and re-infused onto leaves or dissolved into tincture. Other techniques of achieving pure salvinorin A can require more chemistry experience and expensive equipment. They are however unnecessary if being used for personal reasons.


Making non-standardized extract overview:


  1. Leaves are placed in a solvent that can dissolve salvinorin A such as acetone or isopropyl alcohol (acetone can dissolve much more and is a superior solvent) for a certain amount of time depending on purity wanted.
The solvent is then evaporated, leaving a crude extract.
The extract is then placed in a vial and is usually washed with a solvent that can dissolve plant material but not salvinorin A (naphtha).
After repeated washes, the extract is usually clean enough to re-infuse onto papers, it is then dried.
The extract is then redissolved into a fast evaporating solvent (like acetone) and then poured over an amount of leaves. The acetone evaporates leaving the extract onto the leaves.
The final product is a fortified leaf.
Extracts can be regulated by strength. For example, to make 1 gram of 5X strength fortified leaf, one would perform this extraction technique on 4 grams of leaf, and evaporate the crude extract onto 1 gram of leaf (the product is 5 times as strong). This is basically the only method of extracting a decent amount of salvinorin off of the leaves. Other methods such as knocking it off the leaves with a quick water wash produce an incredibly low yield (though much purer).


An excellent guide with pictures about extracting and making fortified leaf (and achieving pure salvinorin A) can be found in the salvia divinorum archive or here.

Forms of Salvia Divinorum

Pictures coming soon.


Salvia Divinorum (as opposed to other salvias) is the only salvia of its potency and psychoactive quality. It comes in different forms such as plain leaf, tincture, and strong extracts. Stronger preparations follow a certain system: the “X” system.



Fresh Leaf


Fresh leaf is mostly used for making a quid of leaves and holding it under the tongue for sublingual absorption. Fresh leaf is preferred for sublingual absorption because it doesn't break up in one's mouth and it's easier to chew.

Dried Leaf

Dried leaf is usually prepared by just taking leaf and leaving it out in the sun. Leaf can also be dried in the oven at about 150 degrees F for however long it takes until they become crispy. Dried salvia leaf is used for smoking. If one plans to use dried leaf for a quid, that person should soak them in water for ten minutes otherwise sublingual absorption can become a disgusting mess. Soaking them in water can lose potency.


Extracts

Salvia divinorum is sold in extracted form as well as leaf. These extracts tend to be more powerful, and more useful if one wants to inhale less smoke. If users aren't satisfied by just plain leaves, they estimate how much of a certain extract they would need to achieve the experience they want. Smoking extracts can result in a much more powerful experience (especially high ones) and can have a quicker onset. This is sometimes preferable because holding in hot salvia smoke isn't always pleasant.


When people see salvia extracts in the form of 5X, 10X, 15X, 21X....etc, it symbolizes exactly what it means. The extract being consumed is that many X times stronger than regular leaves (5X is 5 times as strong as regular leaf). The stronger the extract, typically the stronger the experience; use are your own risk. As far as extraction procedures are concerned, there are two types of these X factor extracts: non-standardized and standardized.


Non-standardized extract

This is done by crudely extracting the psychoactive compounds of salvia along with all its other leaf components and infusing back onto a smaller amount of leaf. This is the most common way of preparing an X extract because it is easier. However, due to the inconsistency of the average amount of salvinorin A in leaf, some extracts with the same X factor can be weaker or stronger than others. For example, making a gram of 5X out of leaves with 2.5mg of sal-a per gram of leaf will be weaker than making a gram of 5X out of leaves with 3.0mg of sal-a per gram of leaf.

Standardized extract

To make standardized extracts, one must first isolate the pure salvinorin A from the leaves (see “Growing and Production of Salvia Divinorum to learn how to do this). The pure chemical is then re-infused onto leaves. The difference between non-standardized is that the same amount will be infused every time. A standardized 5X will always have the same amount of salvinorin A in it since they can regulate how much to put in. These extracts are not only cleaner because there were no impurities thrown in, it is also more expensive because of the process required to get pure salvinorin A.


Tincture

There is also a preparation of tincture. This is made by either dissolving pure salvinorin-A or a semi-pure form of it into ethyl alcohol. It is meant to be used sublingually by holding a certain amount under the tongue for a period of time. This type of preparation tends to cause longer but weaker effects. WARNING: holding strong tincture under the tongue for long periods of time can eventually cause blistering. It is sometimes best to dilute the pure tincture with water although potency may be decreased.


Psychoactive Compounds

Salvia Divinorum contains the Salvinorin compounds A-F. However, out of all these only salvinorin A and salvinorin C are suspected to be psychoactive [citation needed]. Salvinorin A, at the moment, has been concluded to be the main psychoactive ingredient in the salvia divinorum experience. It was isolated by Alfredo Ortega in 1982 in Mexico and in 1984 by Leander J. Valdes III in the United States [citation needed]. Unlike most hallucinogens, salvinorin A is not an alkaloid, it is a trans-neoclerodane diterpenoid (it’s missing a nitrogenous group). Salvinorin A is a selective kappa opioid receptor agonist. It’s also effective at doses as low as 200ug [3], making it the most potent naturally-occurring psychoactive compound. Salvinorin A is also currently the only naturally-occuring nonnitrogenous compound to cause hallucinations via the kappa opioid receptor [4].

Australia

Australia was the first country to prohibit Salvia divinorum and salvinorin A. The committee responsible for the ban has admitted that there is "no evidence of a major public health hazard." The ban went into effect June 1, 2002.

Belgium

On October 18, 2004 the Belgian government added salvinorin A to their list of controlled substances and took effect November 18, 2004. The name of the compound is spelled incorrectly as “salvorine A” in the royal decree that announced the legislative decision.

Brazil

In 2005, Brazilian Customs began enforcing a regulation that prohibits importation of plant products without a permit. Consequently, many people who have shipped Salvia divinorum to Brazil have had the packages returned to them. This only applies to importation.

Canada

In a December 2005 report the Marketed Health Products Directorate, an arm of Health Canada, recommended that Salvia divinorum be placed under the Controlled Drugs and Substances Act. But so far, the Canadian government has not taken any steps to restrict the herb.

Chile

On August 8, 2007, the Chilean government issued a decree making the trafficking of Salvia divinorum and salvinorin A illegal.

Croatia

On April 4, 2008, Salvia divinorum was added to Croatia’s list of controlled substances.

Denmark

Salvia divinorum and salvinorin A have been placed in category B of the Danish list of controlled substances and are only legal for medicinal and scientific purposes. Possession of Salvia divinorum in Denmark now carries a penalty of up to 2 years in prison. The law went into effect on August 23, 2003.

Estonia

The Social Ministry of Estonia has listed Salvia divinorum as a medicinal herb that requires a doctor’s prescription. Some Salvia divinorum vendors have reported that packages sent to Estonia have been returned by customs because of this regulation. This regulation went into effect in April 2005. For documentation, see: Ravimiseaduse (RT I 2005, 2, 4) § 15 lõike 5 punkti 1 alusel.

Finland

In August 2002, Finland passed legislation making it illegal to import Salvia divinorum without a relevant prescription from a doctor.

France

Salvia Divinorum (and salvinorin A) are classified on list I of venimous substances. (http://www.legifrance.gouv.fr/affich...tegorieLien=id)

Germany

On January 23, 2008, the German government proposed that Salvia divinorum (all parts of the plant) be added to Appendix I (Anlage I) of the German narcotics law (Betäubungsmittelgesetz [BtMG]), thereby banning production, trafficking, and possession. This legislation was ratified (reportedly on February 15, 2008) and the new law went into effect on March 1, 2008. The text of the law only mentions Salvia divinorum; salvinorin A is not mentioned.

Iceland

The import of all medicinal herbs requires either a doctor’s prescription or an import license from the health administration.

Italy

January 11, 2005, the Ministry of Health made possession of Salvia divinorum and salvinorin A illegal by placing them in “Tabella 1” of the Tabelle Sostanze Stupefacenti o Psicotrope (Italy's list of prohibited plants and substances).

Japan

On November 9, 2006, the Japanese government decided to add a group of thirty-three drugs to its list of controlled substances. Salvinorin A is one of the newly listed substances. The drugs will be banned under a revised pharmaceutical law, which is expected to take effect in April 2007, and their import, production, and sale except for medical treatment or research purposes will be subject to imprisonment of up to 5 years or a fine of up to five million yen.

Latvia

On May 12, 2009, Latvia added Salvia divinorum to its list of controlled substances, acting on advice from the Ministry of Health.

Lithuania

In 2008 Lithuania added Salvia divinorum to its list of prohibited substances, acting on advice from the Ministry of Health.

Norway

The National Health Council of Norway has listed Salvia divinorum as a medicinal herb that requires a doctor’s prescription. Many Salvia divinorum vendors have reported that packages sent to Norway have been returned by customs because of this regulation. This regulation went into effect 2002.

Poland

On April 6, 2009, President Lech Kaczynski signed an act that added Salvia divinorum to Poland’s list of controlled substances.

Romania

On February 10, 2010, the Government issued an emergency ordinance banning Salvia divinorum.

Russia

In April 2009 Russia’s Surgeon General issued a decree banning the sale of Salvia divinorum and various other psychoactive herbs. On January 14, 2010, the Government announced that it had added Salvia divinorum to a list of controlled substances. This made it illegal to traffic the herb or grow the plant. The regulation does not prohibit mere possession of the herb.

South Korea

An article in the January 14, 2005 edition of the South Korean newspaper Chosun Ilbo reports that South Korea has revised their list of controlled drugs to include Salvia divinorum and salvinorin A. The article does not provide much detail. It is available: here.

Spain

On January 28, 2004 the Spanish Ministry of Health and Consumption issued an order prohibiting the sale of Salvia divinorum, and went into effect on May 6, 2004.

Sweden

Salvinorin A and Salvia divinorum (specifically, any part of the Salvia divinorum plant that contains salvinorin A) have been added to Sweden’s list of controlled substances and went into effect on April 1, 2006.

United Kingdom

On October 19, 2005, John Mann, Member of Parliament, tabled an Early Day Motion (EDM 796) urging the government to ban Salvia divinorum under the provisions of the Misuse of Drugs Act 1971 (Anon. 2005b; Mann 2005). So far, no further steps have been taken to ban Salvia divinorum in the United Kingdom.

The United States

Delaware, Florida, Hawaii, Illinois, Kansas, Kentucky, Louisiana, Minnesota, Mississippi, Missouri, Nebraska, North Carolina, North Dakota, Ohio, Oklahoma, South Dakota, Tennessee, and Virginia are the only states that currently have Salvia divinorum and/or Salvinorin A under Schedule I, which prohibit adults from possessing Salvia divinorum.
West Virginia prohibits possesion of extracts and other processed forms of salvia intended for human consumption, but the law does not apply to unprocessed plant material.
The state of Maine only prohibits possession by minors. Possession remains legal for adults in Maine; however, it is illegal for adults to sell or transfer Salvia divinorum to anyone under 18 years of age.
Maryland prohibits possession by, and sales to, anyone under 21 years of age. A similar law makes it illegal to provide Salvia divinorum to minors in California.
Louisiana, North Carolina, and Tennessee have provisions in their laws that allow possession of the plant when it is not intended for human consumption.
In Wisconsin it is illegal to manufacture, deliver, or sell salvinorin A, but possession is not illegal.
Local laws prohibit possession and sale of Salvia divinorum in Suffolk County, New York and Worcester County, Maryland.
City ordinances prohibit the sale of Salvia divinorum in the towns of West Bridgewater, Massachusetts and Middlebury, Vermont. Similar ordinances prohibit possession and sale of salvia in Ocean City, Maryland and Worland, Wyoming.

In October of 2002, a bill was introduced to the United States Congress that proposed to place Salvia divinorum and salvinorin A in schedule 1 of the Controlled Substances Act. The bill was passed amongst various committees, but no action was taken on it. Ultimately, it died with the dissolution of the 107th Congress at the end of 2002. The author of the bill, Representative Joe Baca of California (democrat), has recently stated that he will not reintroduce the bill.

History of Salvia divinorum

Salvia Divinorum’s origin dates back to the Mazatec Indians in the Sierra Mazateca region of Oaxaca, Mexico. The plant was used there for spiritual as well as physical healing administered by Mazatec Shamans. Jean Basset Johnson first recorded salvia divinorum in 1939 when studying shamanism among the Mazatec community. It was isolated by Alfredo Ortega in 1982 in Mexico. In 1990, Daniel Siebert led a team into this region and documented the psychoactive properties of salvia divinorum. In recent years, it has been spreading around the world. Salvia divinorum hadn't drawn much attention until June 1st, 2002 when Australia became the first country to ban salvia divinorum and its psychoactive compounds. Ever since then many other countries have started to take similar legal action.


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References

  1. ^M. J. Baggott, BA, E. Erowid, F. Erowid, J. E. Mendelson, MD. USE OF SALVIA DIVINORUM, AN UNSCHEDULED HALLUCINOGENIC PLANT: A WEB-BASED SURVEY OF 500 USERS
  2. ^Mowry, M., Mosher, M., Briner, W., 2003. Acute physiologic and chronic glandular trichomes of the psychoactive sage, Salvia divinorum. Annals of histologic changes in rats and mice exposed to the unique hallucinogen Botany 93 (6), 763 – 771.
  3. ^Marushia, Robin (2002) Salvia divinorum: The Botany, Ethnobotany, Biochemistry and Future of a Mexican Mint
  4. ^Bryan L. Roth, Karen Baner, Richard Westkaemper, Daniel Siebert, Kenner C. Rice, SeAnna Steinberg, Paul Ernsberger, Richard B. Rothman. (2002). Salvinorin A: A potent naturally occurring nonnitrogenous k opioid selective agonist

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