Effects of modafinil on attentional processes during 60 hours of sleep deprivation

Modafinil was administrated in doses of 100 mg three times per day during sleep deprivation. Six healthy volunteers participated in a double-blind experiment including two experimental sessions of 7 days each.

The administration of modafinil (300 mg/ 24 h) during sleep deprivation prevents the slowing of serial processes (attentional shifts) and the increasing of errors.