Shared Neural Phenotypes for Mood and Anxiety Disorders

Study Author(s):

Sophia Frangou, MD

Journal Name:

JAMA -Psychiatry Oct. 2019

Publication Date:

9-9-19

PMID:

31664439

Important - Major depressive disorder, bipolar disorder, posttraumatic stress disorder, and anxiety disorders are highly comorbid and have shared clinical features. It is not yet known whether their clinical overlap is reflected at the neurobiological level.

Objective
To detect transdiagnostic convergence in abnormalities in task-related brain activation.

Data Source

Task related fMRI articles published in PubMed, Web of Science, and Google Scholar during the last decade comparing control individuals with patients with mood, posttraumatic stress, and anxiety disorders were examined.