Drug information 2C-E Solubility

My MSDS says 2c-e is soluble in water and ethanol. How soluble it is, I'm not sure. I'm almost positive you could dissolve 500 mgs in 250 ml water and this would then be 2 mgs 2c-e per ml water.

I wouldn't recommend putting more than that into solution if you were planning on dosing SWIM using volumetric dose measuring as 2c-e has a STEEP dose/response curve, as far as I know.
Meaning, the difference between 15 mgs and 20 mgs is huge, for most SWIM's.

Another option is maybe mailing it to SWIM's destination...

Be very careful, messing with customs in many countries could be ugly!

 

Water would prob be a better option as alcohol could be confiscated or looked at more closely just cause it's alcohol. Prob would want the water to be in a small store bought bottle of water, so it would just look like a personal drinking bottle. Make sure no one drinks it by accident! 500mg might be a fatal dose.

 

Dissolve in 20 ml of water or ethanol and put it in a clean amber glaas vial that has been used for medicinal solutions (nose/eye drops). If the MSDS sheet say it (freely) dissolves it will most likely dissolve 100 mg per gram of water or more (ml).

 

This one doesn't say it's freely soluble but "soluble in ethanol, methanol, water".
Now I am curious to find out just how much can be dissolved in h20.

Will look around for info and maybe experiment a little if data is needed.

 

My plan is to disolve 100 mg 2c-e in distilled water. First I will add 100 mg 2c-e to a 250ml graduated cylinder. Then I will fill to the 100ml mark with distilled water. Then stirr/shake until completly disolved. Creating a 1mg:1ml ratio. Then using a 10ml volumetric pipet will transfer 5ml to 2 dram vials(1 dram=3.6 ml) for storage. Each vial will contain 5 ml soultion containg 5 mg 2c-e. I am a light weight and having 5mg doses ready will be handy!

 

A friend of mine dissolved 500mg into 250ml of distilled water. Most of it seemed to dissolve, but there were enough flakes on the bottom that he shook it each time before measuring any out just to be sure.

It was kept in the fridge and still seemed potent after six months. He once left a smaller amount of the solution (same concentration) in a mason jar in a hot car for over 48 hours. If anything, it seemed more potent afterwards (probably some water had evaporated). 2C-E doesn't seem nearly as fragile as some other chemicals. The chemicals in tap water would probably harm it, however.

I'm sure said friend would be curious about the soluability and viability of an ethanol solution, if anyone has friends with experience in this regard.


ECL

 

just the other night, I made a 25mL solution of 200mg 2c-e and distilled water, which gives a concentration of 8mg/mL. The solution was noticeably cloudy, but there were no particles floating about.

 

I reply to that 2c-e water solution concentration.

I made lengthy tests with distilled water and 2c-e powder and 2c-e hcl is highly soluble to water. Saturation concentration is hovering somewhere around 50mg/ml in normal room temperatures. 40mg/ml is very stable and crystallizes only below 5C degrees. It is also very stable in distilled water solution, 3 years old liquid bottle has lost only 20-30% of its potency over years. High concentration solutions need some heat to get it dissolved, but once it is dissolved, it will not crystallize back.

 

2C-E Solubility in Water ?

Hi,
I am acquiring 2C-E sometime soon and I don't have his own milligram scale.
I will use dH2O to know how much he would need to take. To do that however, I need to know how much 2C-E is soluble in water.
I am getting 250mg and thought about dissolving it into 250mL or, if possible, less. 125mL would be good, that would mean 10mL = 20mg. I have no problem with taste at all. The less water the better.


SWIM's question is : How soluble is 2C-E in water ?

Thanks a lot.

 

Re: 2C-E Solubility in Water ?

You needs to find a way to weight the total mass as it is unlikely it will be exactly 250mg. As the HCl, 2c-e should be rather freely soluble in dh2o. I would likely do aroung 10mg/ml, but is really whatever is easy to measure.

The main thing is weighing the powder b4 volumetric dosing.

 

Re: 2C-E Solubility in Water ?

remember also that if it does not dissolve in the liquid fully at first, wait before adding more water, swim found lemon juice helps the process.

and be sure the weight is precisely what you need (ie requiring a good scale)


2c-e will rock swiy's socks off, start low and work your way up 15mg seems small, but it goes a long way.

 

Re: 2C-E Solubility in Water ?

Thanks a lot to you two yous. I will test the weigh with a .01g scale. I know it's not very precise but the doses shouldn't vary of more than 1 or 2mg using that way (I know it's a lot, but my dog is very strong minded and experimented with psychedelics).

UPDATE : I used 5mg/mL. Could have been a lot more concentrated. I had no difficulties at all dissolving it.

 

Re: 2C-E Solubility in Water ?

Thanks for the info One thing i was wondering was if you have 2c-e in distilled water for storage? say you don't have a mg scale and you dumped the whole thing in a certain amount of distilled water, so you can figure out the dosage. does the compound change over time? or is it pretty stable?

 

Re: 2C-E Solubility in Water ?

2c-e should be very stable and is unlikely to "change" or degrade over time.

If by "the whole thing" you mean a quantity received from a vendor please be aware that vendors have been known to make mistakes and send out too little, or way too much product...

 

2c-e- 15mg soluble in 1ml dH2o?

Anybody know? Thanks!

 

Re: 2c-e- 15mg soluble in 1ml dH2o?

My Buddha statue once told me, he can get 10mg/mL.

 

Re: 2c-e- 15mg soluble in 1ml dH2o?

My lab monkey tested this a lot and the maximum they were able to make soluble was 52mg/ml for pure 2c-e HCl and distilled water. This requires considerable time, some heating and considerable shaking of the mixture. Slight heating (up to 50-60C) helps the solution to homogenize. This amount took some 2 hours to dissolve. Normal solution they made was 42mg/ml, which took 10-30min to dissolve with only a slight heating and shaking. 15mg is easily soluble to normal tap water if 2c-e is HCl salt. Measure water, powder, mix and shake a few minutes, should be fine. Distilled water is better if you plan to keep the solution in storage for longer time, impurities tend to have negative effects on stability of most mixtures.

 

Re: 2C-E Solubility in Water ?

I was also wanting to know if you can do this and put it on blotter?
please let me know! I will want to desolve 1 grm into X amount of dh2o? to make 70 blotters?
swim thanks all who reply!

 

Re: 2C-E Solubility in Water ?

2c-e blotters wouldn't work, as far as Squirrel knows. Measuring with a .01 scale and then dissolving into large amounts of water (so its not fiddly/unreliable with doses) will work just fine