Desipramine (Norpramin, Pertofane) is a tricyclic antidepressant (TCA). It inhibits the reuptake of norepinephrine and to a lesser extent serotonin . It is used to treat depression and insomnia.
Chemistry of Desipramine
[1]
Column 1 Column 2 Systematic (IUPAC) name: 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine Synonyms: 10,11-dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepine, 5-([gamma]-methylaminopropyl)-iminodibenzyl, N-(3-methylaminopropyl)iminodibenzyl, desmethylimipramine, norimipramine; G-35020, JB-8181, NSC-114901, Norpramin, Nortimil, Pertofran, Pertofrane, Petylyl (hydrochloride) Molecular Formula: C18H22N2 Molar mass: 266.39 g/mol, 302.85 g/mol (hydrochloride) CAS Registry Number: 50-47-5, 58-28-6 (hydrochloride) Melting Point: 215-216°C (hydrochloride) Boiling Point: 172-174°C @ 0.02 mmHg Flash Point: no data Solubility: Freely soluble in methanol, chloroform. Soluble in water, alcohol. Insoluble in ether. Additionnal data: none Notes: White to off white crystals from methanol