Drug information Methylenedioxypyrovalerone (MDPV) Drug Info

Discussion in 'Beta-Ketones' started by dr.red.evil, Aug 1, 2005.

  1. Expat98

    Expat98 Platinum Member & Advisor

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    Re: Mdpv

    The ironic part is that the euphoria from MDPV is mild at best and often completely non-existent. Most people who go on binges report that they feel strangely compelled to keep using it even though they're not sure if they're really enjoying it. What a weird drug. At least with heroin, methamphtamine and crack the feelings of enjoyment are clear enough, and they don't sneak up on you and hit you with a terrible panic attack and feeling like you're about to die if you overdo it just a tiny bit.

    Could not agree more. As a recreational drug, the downside FAR outweighs the upside.
     
  2. G_nome

    G_nome Palladium Member

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    Re: Mdpv

    Swim only ever really enjoyed mdpv in combination with opiates and/or benzos. Swim says it's horrible by itself, panic attack city, and even though he wasn't enjoying it for most of the binge he still stayed up for 3 days til it was all gone the last time he had some.
    Very strange shit. Probably the only drug swim ever regrets doing.
    Do any swimmers know if a 3 day binge 4-5 weeks ago could be responsible for panic attacks and waking up anxious ever since?
     
  3. dr ACE

    dr ACE Titanium Member

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    Re: Mdpv

    yes very possibly, probably due to dopaime deficiency try taking mutivitamins,Vitamin B6, Tyrosine and
    eating healthily should help
     
    Last edited: Apr 10, 2010
  4. G_nome

    G_nome Palladium Member

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    Re: Mdpv

    Thanks, dr.

    I got some multi-vitamins & minerals 2 days ago, shortly after taking one he was feeling better than he has in long time, but also a bit manic. Dunno if it was because of them though, as yesterday I had a really bad panic attack, no trigger. But it won't do him any harm in continuing to take them, if they do help with that or not.
    I was also considering getting some more Tyrosine again, he was taking that for 4-6 weeks during and after a recent opiate detox, has never felt so good in all his life, was only directly following that 3 day mdpv binge that everything changed, like it just consumed and blackened his soul.
    I could probably do with seeing a professional about all this, but he hasn't had much luck with them in the past and it's kinda scary the pain that talking about shit in swim's life may bring up.
    But yeah, thanks for the suggestions. Did You mean to say eating though, rather than heating?
     
  5. dr ACE

    dr ACE Titanium Member

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    Re: Mdpv

    yea he sure did, good heating allways helps not the lecy bill though lol
     
  6. Nnizzle

    Nnizzle Gold Member

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    Re: Mdpv

    A friend doesn't know what the issue everyone else is having with MDPV. Yes I do sometimes feel like redose would be nice but he finds the thought to be easily suppressed. Plus he has found that redose doesn't really do much anyway except for exacerbate jitteriness. He has not had any trouble dosing one time, once every three or four days for the past two or three months (always insufflated, 5-10mg). To each his own though. One thing he has found is that while the comedown is not dysphoric or uncomfortable he does get VERY tired.

    He did really relate to the post
    Someone has found that sometimes he will feel a tightness in his left breast and an odd feeling in the back of his head if he takes a mg or two too much. He recently had an anxiety attack (his first and only) but it was nearly 7 hours after comedown of last dose. The tightness actually is still sort of present during sober life but seems to sometimes be exacerbated by MDPV and he has found that the head feeling also seems to be the same, so he has basically decided that it is all a product of anxiety rather than physiological effects as a result of MDPV.

    He remembers his first dose though, which was VERY pleasurable which doesn't seem to really be the case anymore. It is not unpleasurable but euphoria is minimal if pleasant at all. He has not taken more than a week's break from stimulants (including amphetamines, etc.) for about 6 months so perhaps this is the issue. But he uses stimulants for productivity rather than pleasure... that's what MDMA is for :).

    Finally from his use he has found that insufflation seems to be the only viable ROA. Oral produces absolutely nothing, and perhaps sublingual sometimes is a bit effective but by far insufflation produces the best results. Ketones (methylenedioxypyrovalerONE) are quite subject to degradation so he guesses that MDPV is rather quickly inactivated by water as others have mentioned, that includes water e.g. in saliva and throughout the stomach and intestinal tract.
     
  7. RJTstoke

    RJTstoke Newbie

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    does any body have any ideas as to how you are to handle the comedown on this salty old seadog mdvp because its got me rattling like an a reg maestro!!!!!!
     
  8. Love4TheWeekend

    Love4TheWeekend Silver Member

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    ^^^ A really good cry helps. No joke. One of those heaving sobbing pile of tears cries.

    EDIT:: I think some folks may think I'm playin around but SWIM once found himself on a mean comedown from peevee and the tears just started flowing. So he let the anxiety and emotion flow too. Someone more biochemically savvy than I may be able to explain why, but it helped immensely and I was able to relax and even sleep peacefully shortly thereafter.
     
    Last edited: Jul 23, 2010
  9. G_nome

    G_nome Palladium Member

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    Focus on swiy's breathing, try and slow that down a bit.
    Chamomile tea, benzos or opiates all helped a friend's sister's budgie come down a lot easier on this substance.
    The same budgie has also found that smoking a small amount of 5-MeO-DALT really helps in getting rid of all that anxiety and shakiness an stuff, but You might not have the same effects.
    Swim adds that a nice Indica may help too.

    If You has none of the above then swim's afraid You is just gonna have to ride it out. Swiy's just got to remember that it will wear off, eventually.

    All the best to swiy.
     
  10. EricB

    EricB Newbie

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    My turtle tried it several times : she bought a gram in june.
    As said before, no euphoria at all, only racing heart + turtle unable to sleep for 2 days...
    Good if you want to stay awake but no recreational value in turtle's opinion
     
  11. smokesmydope

    smokesmydope Newbie

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    there are so many chemicals being researched now that I has become confused as to which is the closest to mdpv?
     
  12. DR. PHD

    DR. PHD Silver Member

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    Forgive my lack of knowledge but are ketones the same as or related to ketamine?
     
  13. Terrapinzflyer

    Terrapinzflyer MDMA, RC & News Forums Platinum Member & Advisor

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    ^^ Short answer (as I haven't had my coffee yet) NO. Absolutely no relation.
     
  14. Tamis

    Tamis Titanium Member

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    My star keeper recently played with the devil.... (mdpv)

    This is an extremly strange product, it is not something that you can take often and control, anyone who uses daily is on for the worst ride of their life with a possible dramatic conclusion :/

    If one wishes to use it recreationnaly, he will not escape the nasty side effects... this is why almost everyone combines it with benzos or opiates to counteract the norepinephrine effects.

    The product dose and redose response curve is one of its kind, a few more mg on a redose might greatly change your ability to sleep for A LOT of hours while in a very dysphoric overstimulated state. The research that would be needed to "control" this aspect is life threatening and should not be done if you value your life ! It seems mdpv affects its own metabolism over the course of redoses, NEVER forget this "detail".

    The initial euphoric high is very mild and nice, so easy to control and apparently absolutely safe :) It is not !!
    This euphoria will not be attained again in the session, careless redosing to chase it will lead to severe side effects !

    Binging will lead to parkisonian symptoms and psychosis even if sleeping a little, it takes a while to get there but anyone overdoing it will get there !
    Vision will be blurry (THIS IS A CLEAR STOP/THROW AWAY SIGN), stange tremors, writing is like parkisonian patients ! People if you get blurry vision and that your hand writing does not look like yours (very tiny, unreadable almost), if you keep pushing, you are almost 100% sure to fall into psychosis, the trouble is you wont realize it, it totaly blends with reality !

    Another problem is that users tend to ingest HUGE quantities of benzos that lead to the classical problems linked to benzos addiction, no one with half a brain would want that !

    This is a product my star keeper controls only because he saw the abyss once ! He controls because he uses at most once a month, with a mg scale and goes with very small quantities. It is actually not very fun used this way, but is a great tool for lots of tasks !

    There are no safe ways to use this product for recreationnal purposes !
     
  15. BurtonBaton

    BurtonBaton Newbie

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    My lab monkey has been through hell and back with MDPV, but I think I've found the key to giving him a good experience. If I feed my monkey omeprazole (Prilosec) with his MDPV, his panic attacks are non-existent. My theory is that MDPV opens the sphincter between my monkey's esophagus and stomach, causing stomach acid to shoot up into his esophagus and cause chest pain. Omeprazole makes his stomach produce less acid, so it won't shoot up into the esophagus.

    My monkey has been taking omeprazole in combination with MDPV every day for the last month, and has not had a single panic attack. His blood pressure is 140/100 on MDPV, which is high but certainly not worth a trip to the vet. To be safe, I also make sure he sleeps at least once every two days. And to avoid the comedown, I feed him a Seroquel, which usually puts him out in under 30 minutes even if I had just given him some MDPV.

    Omeprazole is available over the counter as Prilosec OTC, but Seroquel is expensive and a lot harder to get. Any antipsychotic will do though.
     
  16. Tamis

    Tamis Titanium Member

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    burtonbaton is right, there is a clear increase in stomach acidity which is partly responsible for chest discomfort. Baking soda mixed with water does make things better.

    We end up with the same conclusion, mdpv "needs" to be combined with other products to cope with the side-effects...
     
  17. top_hat

    top_hat Newbie

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    This is SWIM's MDPV trip report

    I am ~150lbs, early 20's, good to excellent physical health, resting heart rate 81

    (Water and milk to stay hydrated, fruit and a taco for sustenance)

    10pm
    t+0:00 oral 14mg dose, experience with stims factored in

    t+0:20 SWIM can already tell MDPV has pronouncedly distinct effects from other stimulants, cocaine, amphetamines, caffeine.. MDPV's effects subtle, get the feeling much lies under the surface

    t+1:00 Very subtle euphoria and a general feeling of well being
    very social, speach flows easily and with a natural calm. Contrasts with cocaines overflowing dam of gab. Noticing unusually calm for SWIM being stimulated but definately up:)

    t+1:10 No internal alarms and pulse 108, there goes another 7mg orally

    t+1:25 Unexpected adventure! SWIM's gf shows up wanting to go take SWIM to some food (excuse to check in on SWIM and his new substance perhaps...)

    t+1:35 "Calm as a bomb" stimulated like I could run 40 miles but content to sit and talk with gf

    (rest of trip spent chilln at my apt alone on my compy)

    t+3:30 No real craving but something about MDPV recommended SWIM keep the path with 5mg

    t+4:00 Phenazepam 4mg eaten to deal with odd feelings arising

    t+4:30 This is where a wise You might call it a night... lay in bed, absolutely no interest in sleep.

    4 AM

    t+6:00 SWIM's feeling out of it, not a bad emotional comedown, just slightly uncoordinated, also speech effected

    4 AM - 12:01PM
    t+6:00-11:00 Bumps of 5 mg consumed as SMIM desired cruising the internet reading and chatting

    <!> SWIM bumped 2mg then spontaneously went to gym in the apt complex at about 5 am ultra weary of cardiovascular mishaps, resting pulse 106 max pulse recorded 158 wearing personal heart monitor (after 3 sets of 12 reps dumbell press @ 70% max 1 rep)
    <!>

    <!>DO NOT DUPLICATE, THIS IS PROBABLY EXTREMELY BAD FOR YOUR CARDIOVASCULAR SYSTEM, SPECIFICALLY YOUR HEART<!>

    Total MDPV Ingested :~50mg

    Reflection, initial dose(s) were fun and got some chores done(next time will stop at this point, there is little to no fun to be had past the first 2-3 doses)... but this last 6 hours just kept SWIM awake and at 80% of mental capacity.. also after some reading this shit is very bad on your heart... my recommendation stay away

    -=Update=-
    Hi! SWIM forgot to mention maintenance use of phenazepam so just wanted you all to know

    -=Update: 2 Days Later=-
    I am @ 100% physical and mental :laugh:. Went to uni. clinic (excellent facility) and was EKG'd, pulse, and ultrasound in important areas. I was quite happy (nervous before).

    Also, with more reading done it appears that MDPV is bad for you's heart but not nearly as thought before (Definitely less than Cocaine, possibly less/similar to amphetamines).

    MDPV molecule is not cardiotoxic, nor its metabolites. The cardiovascular dangers of MDPV are likely prolonged tachycardia (high pulse) and (unlikely) vessel bustin' high blood pressure.
     
  18. snapper

    snapper Gold Member

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    SWIM also experiences severe stomach acid overproduction with MDPV but I get this with every stimulant I have used. SWIM usually takes pepcid for shorter useages and also will use omeprazole when SWIM binges. I want to point out that for omeprazole to work it needs to be taken as a course rather than as a single use. For rapid stomach acid management I takes 20 mg pepcid, waits an hour then takes something chalky like tums. This works fast and provides quick relief.
     
  19. Tamis

    Tamis Titanium Member

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    I rarelly say this (rep- if you wish people), but this is just so fucking stupid... one of the worst idea possible !

    Does swiy have a death wish ??
     
  20. monstercookie

    monstercookie Silver Member

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    Curious about this substance and trying to find out more information as to the names it goes by in the wider public.

    Is the chemical name associated to a product called Plan B and is this in anyway related to Ivory Wave?

    I am trying to gauge how many variations have appeared of a base chemical and how many more mixes are being produced (my theory is a lot of this comes from the eastern block labs or the formulas end up in the UK where I am based).

    Thanks in advance and thanks for the info so far!