2C-C (4-chloro-2,5-dimethoxyphenethylamine) is a psychedelic phenethylamine first described by chemist Alexander Shulgin in his book PiHKAL: A Chemical Love Story. 2C-C is a fairly short acting hallucinogen, lasting between 4-6 hours and is usually taken orally with a typical dose of 20-40mg. 2C-C has both hallucinogenic and entactogenic properties, and is often described as a less intense and more forgiving psychedelic experience than other phenethylamines.

Introduction to 2C-C

[​IMG]Initally described by Alexander Shulgin as a facinating compound, 2C-C is a coniderably strong, yet short acting psycedelic hallucinogen which produces effects similar to that of other psycedelics hallucinogens such as psilocybin, LSD, and mescaline. 2C-C belongs to the family of 2C compounds which are a group of phenethylamines that all produce similar, yet not quite identical hallucinogenic effects. 2C-C works by stimulating monoamine receptor activity and inhibiting the reuptake of serotonin and norepinephrine with IC50 values of 31 uM for serotonin and 63 uM for norepinephrine.

Using 2C-C

2C-C Dosage Chart
Column 1 Column 2
Threshold 1-15 mg
Light 10-25 mg
Moderate 25-35 mg
Strong 35-50 mg

Ways of administration

2C-C is most commonly administered through oral consumption, however there have been reports of users insufflating the compound. Let it be noted that upon insufflation of 2C-C, it is very common for an extremely painful burning sensation to occur.

Effects of 2C-C


  • Euphoria
  • Feelings of empathy
  • Feelings of closeness with others
  • Sedation


  • Open & closed eye hallucinations
  • Auditory Distortions


Combinations with 2C-C

Different Uses for 2C-C

Pharmacology of 2C-C

2C-C functions by stimulating monoamine receptor activity as well as acting as an inhibitor for the reuptake of serotonin and norepinephrine, with IC50 values of 31 uM for serotonin and 63 uM for norepinephrine.

Chemistry of 2C-C

Column 1 Column 2
Systematic(IUPAC) name: 4-chloro-2,5-dimethoxy-benzeneethanamine
Synonyms: 2,5-dimethoxy-4-chlorophenethylamine, 1-(4-Chloro-2,5-dimethoxyphenyl)-2-ethanamine, 1-(4-chloro-2,5-dimethoxyphenyl)-2-aminoethane
Molecular Formula: C10H14ClNO2, C10H14ClNO2.HCl
Molar mass: 215.68 g/mol, 252.14 g/mol (hydrochloride) [1]
CAS Registry Number: 88441-14-9
Melting Point: 223.3°C [2], 220-221°C (not referenced)
Boiling Point: no data
Flash Point: no data
Solubility: no data
Additionnal data: no data
Notes: Hydrochloride aspect: beige powder [2]

Reagent test results of 2C-C

Reagent color produced picture video
Marquis Lime[1] link (reference); link (results) -
Mandelin Biege[1] link (reference); link (results) -
Mecke Biege[1] link (reference); link (results) -
Cobalt thiocyanate Pink (no reaction)[1] - -

The dangers of 2C-C

There are several dangers involving 2C-C which should be brought to ones attention prior to the compounds administration...
  • 2C-C is a research chemical, thus the short term and long term effects have yet to be identified through any sort of formal trials.
  • 2C-C is a strong psychoactive drug, users whom have a know mental illness should avoid this compound as it may result in undesirable symptoms related to such mental illness.
These are the dangers common to all psychedelic drugs:

Accidental injury.
When on a psychedelic drug, it is easier to accidentally injure yourself. Also because of the disorientating and potentially delusion inspiring nature of the experience, you could be lead to inflict harm on others or yourself. People have fallen off rooftops, run into traffic, attempted to throw people off rooftops as 'sacrifices', drowned, and so on. The best way of protecting against this is to have a friend with you who is sober to look after you and handle any negative situation that might arise.

Bad trips. A bad trip is a negative psychedelic experience. It can range from a mildly negative feeling of anxiety/discomfort, to full-blown psychosis. Bad trips usually ruin a psychedelic experience for the tripper and everyone else. Most bad trips are manageable, just very uncomfortable and difficult. Some are extreme and unmanageable though. It's not uncommon for a bad trip to result in lingering psychological issues. Usually just a few days of negative emotions and anxiety. Sometimes, however, a week or so of serious anxiety, destabilized mental state and impaired functioning is possible. On very rare occasions, a month or two of severely diminished functioning, traumatized mental state, depression & crippling anxiety can occur. More information on bad trips can be found here. The best way of avoiding a bad trip is having the correct set and setting.

Permanent psychosis. Psychedelics are believed by researchers not to cause permanent psychosis, however they could trigger a latent mental illness in someone who was already predisposed to it, or make existing mental illnesses worse. If there is a history of mental illness in your family, you are more likely to be predisposed. Everyone is at some risk, however.

PTSD, anxiety disorder, depression & depersonalization. There are anecdotal reports of the trauma inflicted by some bad trips leading to depression and anxiety which while usually temporary, could potentially develop into lasting disorders. While no different to the potential of any traumatic event to cause lasting disorders, nonetheless this is a danger of psychedelic drug use.

Producing 2C-C

Forms of 2C-C

2C-C is commonly available in both its hydrochloride and hydrobromide salts forms.

2C-C (Unknown form)

United Nations


As of July 2012, 2C-C is listed as a schedule I controlled substance in the United States, covered under the Food and Drug Administrations "Safety and Innovation Act".


United Kingdom

2C-C is a class A controlled substance as it is covered by the phenethylamine derivatives clause of the Misuse of Drugs Act 1971.

Other Countries


As of March 1st, 2005, 2C-C is classified under the "Lag (1999:42) om förbud mot vissa hälsofarliga varor" as a hazardous substance making it illegal to posses.


As of December 2008, 2C-C is considered to be a controlled substance in Israel.


2C-C falls under Japans Pharmaceutical Affairs Law as a Designated Substance making it illegal to posses.

History of 2C-C

More 2C-C Sections

The latest 2C-C threads


  1. ^ a b c dhttp://www.reagent-base.net/reagents-table/

[1] Calculated from Atomic Weights of the Elements, 2007
[2] 2C-C monograph

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