Introduction to Alpha-Methyltryptamine


Using Alpha-Methyltryptamine

Vendors and online reports stress the fact that aMT is active from very small doses as low as 10mg oral or even 2mg when smoked so caution should be taken to correctly measure doses especially when smoking.

aMT is well known for its long duration of action typically in the 10-12 hour range, although 24 hour+ experiences are not unheard of. Users should take the long duration into account when scheduling such an experience

Ways of administration

aMT can be taken:

orally with dosage ranging from 10mg (threshold dose) to 100mg (extremely strong experience)

Smoked with dosage ranging from 2-4mg to 20mg. Onset is much faster than oral administration

It has been reported that insufflation of aMT produces much weaker effects and that this method of administration is fairly painful.
It has also been suggested that this route of administration is ineffective due to aMT freebass, the commonly available form, is insoluable in water, making absorbtion VIA mucus membranes ineffective.

Effects of Alpha-Methyltryptamine

The effects of aMT vary considerably depending on dosage and route of administration.
Reports suggest weak doses (below 50-60mg) taken orally produce a stimulating 'speedy' effect with a noticable body load.
Higher doses (60mg+) have been reported to produce varying degrees of psychadelic visuals.
Reports state that doses of 100mg+ are too strong and overwhelming for inexperienced users without tollerance. These reports speak of considerable side effects. The onset of orally administered aMT can take as long as two hours so users should avoid redosing until sufficient time has passed to fully judge their level of intoxication.

Smoking aMT is reported to produce less psychadelic effects and more stimulant style effects with both a faster onset and a shorter duration. Care should be taken with measuring doses as aMT is considerably more potent by weight when smoked.

Combinations with Alpha-Methyltryptamine

Anecdotal reports suggest cannabis can potentiate the psychadelic effects of aMT

Different Uses for Alpha-Methyltryptamine

Alpha-methyltryptamine was originaly used as an anti-depressant in the 1960's.

Annecdotal reports suggest aMT functions well as an anti-depressant at doses of around 5mg daily

Pharmacology of Alpha-Methyltryptamine

From Wikipedia:

Chemistry of Alpha-Methyltryptamine

From Wikipedia:

Column 1 Column 2
Systematic(IUPAC) name: 2-(1H-Indol-3-yl)-1-methyl-ethylamine
Synonyms: -methyl-1H-indole-3-ethanamine, 3-(2-aminopropyl)indole, 1-(1H-Indol-3-yl)propan-2-amine, AMT, Indopan, IT-290, IT-403, U-14,164E, 3-IT
Molecular Formula: C11H14N18
Molar mass: 174.24 g/mol [2]
CAS Registry Number: 299-26-3 (freebase), 7795-51-9 ((S)-form), 7795-52-0 ((R)-form), 21463-31-0 (hydrochloride)
Melting Point: 101-102°C, also reported 98-99°C; 125-126°C ((S)-form), 126-127°C ((R)-form)
Boiling Point: no data
Flash Point: no data
Solubility: no data
Additionnal data: none
Notes: Racemate aspect : white powder; crystallized from diethyl ether. (S)-form crystallized from ethyl acetate/hexane

The dangers of Alpha-Methyltryptamine

From Wikipedia:

aMT in conjunction with SSRI/SNRI medication can precipitate serotonin syndrome. The initial symptoms of which are easily confused with normal aMT effects and side effects. Overdose can be fatal if serotonin shock is induced and not recognised and dealt with both quickly and effectively.

The muscle tensions induced can lead to rhabdomyolysis.

From Wikipedia:

Producing Alpha-Methyltryptamine

Information provided by Iggypoop in the aMT info thread

Forms of Alpha-Methyltryptamine

Alpha-methyltryptamine freebase is available in:

powder form: it is a fine powder Orange in colour

'Pellet' form, typically 30mg aMT freebase: small blue pellet.

Legal status of Alpha-Methyltryptamine

United Nations


αMT is a Schedule I controlled substance in the Controlled Substances Act of the United States. On Jan 28th, 2003, the DEA announced its intent to emergency schedule AMT. On April 4, 2003, they issued their final order to temporarily place AMT in Schedule I. The temporary scheduling lasted 18 months and on Sep 29, 2004, AMT was placed formally into Schedule I.


Alpha-methyltryptamine was banned in the United Kingdom in early 2015 under new legislation that also banned 5-MeO-DALT. It is also prohibited in Ireland.

Other Countries


αMT is reported to be a schedule 8 controlled drug in Australia, though this is unconfirmed. It is known that 5-MeO-αMT is schedule 9 in Australia however.

History of Alpha-Methyltryptamine

From wikipedia:

The latest Alpha-Methyltryptamine threads


[1]Merck Index, fifteenth edition (2013)
[2]Calculated from Atomic Weights of the Elements, 2007

This page has been seen 68,962 times.