Introduction to DPT

Initially reported in 1973, DPT produces a wide range of psychedelic effects through several modes of action including reuptake inhibition and antagonism of the serotonin, dopamine, and norepinephrine receptors. The majority of DPT effects are derived from the antagonism of the 5-HT2A serotonin receptor, though its antagonistic properties for the 5-HT1A serotonin receptor also show that modulation of this receptor highly influences the actions of DPT as well.

The duration of DPT can vary from anywhere between 30 minutes to 4 hours depending on the route of administration which is utilized, likewise the time of onset is also very dependent on the route of administration, ranging in duration from almost immediately to upwards of 1 hour.

Using DPT

Ways of Administration

DPT can be administered through a variety of different routes with some being more potent than others as a result of bioavailability and the physical properties of the compound. Oral, intranasal, intramuscular, and vaporization all prove to be viable routes of administration for DPT with oral administration being the weaker of the four routes.

Oral

Column 1	Column 2
Threshold/Light	75-150 mg
Moderate	150-250 mg
Strong	200-350 mg

Intranasal

Column 1	Column 2
Threshold/Light	5-20 mg
Moderate	20-100 mg
Strong	60-200 mg

Intramuscular Injection

Column 1	Column 2
Threshold/Light	5-10 mg
Moderate	15-75 mg
Strong	50-125 mg

Vaporization/Smoked

Column 1	Column 2
Threshold/Light	5-10 mg
Moderate	20-50 mg
Strong	50-100 mg

Effects of DPT

Positive

• Increased musical appreciation
• Increased color vibrancy
• Pleasant sensation of inner warmth

Neutral

• Closed and open eyed hallucinations
• Buzzing/vibrating feeling of the body
• Loss of boundaries
• Synaesthesia
• Out of body experiences

Negative

• Ego Death
• Psychedelic crisis
• Nausea/vomiting

Chemistry of DPT

Column 1	Column 2
Systematic(IUPAC) name:	3-[2-(dipropylamino)ethyl]indole
Synonyms:	DPT
Molecular Formula:	C16H24N2
Molar mass:	244.38
CAS Registry Number:	16382-06-2
Melting Point:	174.5-178°C
Boiling Point:	387.4°C
Flash Point:	188.1°C
Solubility:	as freebase: ~3 mg/ml in PBS, ~13 mg/ml in EtOH, ~14 mg/ml in DMSO, ~11 mg/ml in DMF

The Dangers of DPT

As with any psychoactive substance DPT carries its own risks and dangers which should always be considered before the drug is administered.

• Little information has formally been determined on the effects and side effects of DPT simply due to the lack of clinical trials performed on the compound.
• With DPT being active through various routes of administration, caution should be used when experimenting with different routes as the dosages may not carry from one route to the next.

These are the dangers common to all psychedelic drugs:

Accidental injury. When on a psychedelic drug, it is easier to accidentally injure yourself. Also because of the disorientating and potentially delusion inspiring nature of the experience, you could be lead to inflict harm on others or yourself. People have fallen off rooftops, run into traffic, attempted to throw people off rooftops as 'sacrifices', drowned, and so on. The best way of protecting against this is to have a friend with you who is sober to look after you and handle any negative situation that might arise.

Bad trips. A bad trip is a negative psychedelic experience. It can range from a mildly negative feeling of anxiety/discomfort, to full-blown psychosis. Bad trips usually ruin a psychedelic experience for the tripper and everyone else. Most bad trips are manageable, just very uncomfortable and difficult. Some are extreme and unmanageable though. It's not uncommon for a bad trip to result in lingering psychological issues. Usually just a few days of negative emotions and anxiety. Sometimes, however, a week or so of serious anxiety, destabilized mental state and impaired functioning is possible. On very rare occasions, a month or two of severely diminished functioning, traumatized mental state, depression & crippling anxiety can occur. More information on bad trips can be found here. The best way of avoiding a bad trip is having the correct set and setting.

Permanent psychosis. Psychedelics are believed by researchers not to cause permanent psychosis, however they could trigger a latent mental illness in someone who was already predisposed to it, or make existing mental illnesses worse. If there is a history of mental illness in your family, you are more likely to be predisposed. Everyone is at some risk, however.

PTSD, anxiety disorder, depression & depersonalization. There are anecdotal reports of the trauma inflicted by some bad trips leading to depression and anxiety which while usually temporary, could potentially develop into lasting disorders. While no different to the potential of any traumatic event to cause lasting disorders, nonetheless this is a danger of psychedelic drug use.

Legal Status of DPT

United Nations

USA

DPT is not scheduled in the United States as a country, however individual state law may differ.
DPT is scheduled as a Schedule I controlled substance in the state of Florida.
DPT is listed as a Scheduled substance in the state of Maine.

UK

DPT is listed as a Class A drug in the UK, caught under the tryptamine clause in the Misuse of Drugs Act which states... "Any compound...structurally derived from tryptamine or from a ring-hydroxy tryptamine by substitution at the nitrogen atom of the sidechain with one or more alkyl substituents but with no other substituent."

EU

Other Countries

Belgium

DPT is listed as a controlled substance in the country of Belgium making it illegal to posses, buy, sell, or manufacture.

Greece

As of Feb 18, 2003 DPT is considered to be a controlled substance in the country of Greece.

Japan

DPT is listed as a designer substance covered under the Pharmaceutical Affairs Law in the country of Japan.

Portugal

DPT is listed under Table II-A in the "tables of plants, substances, and preparations subject to control" law in the country of Portugal.

DPT

References