6-APDB also known as 6-(2-Aminopropyl)-2,3-dihydrobenzofuran is a stimulant, psychedelic, and empathogen of the phenethylamine class producing effects similar to that of MDA.
Introduction to 6-APDB
Structurally speaking, 6-APDB is an analog of MDA differing only by the substitution of a methylene bridge in place of the heterocyclic 4-position oxygen from the 3,4-methylenedioxy ring. As with 5-APDB, 6-APDB was first synthesised by David E. Nichols in the early 1990 as part of an investigative research study on non-neurotoxic MDMA analogs. In terms of its pharmacodynamic action, 6-APDB acts as a triple reuptake inhibitor with IC50 valves at 322 nM for serotonin, 1,997 nM for dopamine, and 980 nM for norepinephrine.
Using 6-APDB
Ways of Administration
6-APDB can be administered through a variety of different routes, the most common of which are oral consumption and intranasal insufflation. Oral consumption appears to be the primary route of administration among researcher, due most likely to the consistency and duration of the effects as the result of an increased bioavailability which stems from the dense concentration of 5HT serotonin receptors which line the walls of the gastrointestinal tract.Effects of 6-APDB
Positive
- Euphoria
- Feelings of love and empathy
- Stimulation
- Increased sensory awareness
- Increased musical appreciation
- Elevated mood
Neutral
- Nystagmus
- Mild visual distortions
- Mild visual hallucinations (open and closed eye)
Negative
- Hyperthermia
- Restlessness
- Anxiety
- Tachycardia
- Bruxism
Chemistry of 6-APDB
Column 1 Column 2 Systematic(IUPAC) name: 1-(2,3-dihydro-1-benzofuran-6-yl)propan-2-amine Synonyms: EMA-3, 4-desoxy-MDA, 6-(2-Aminopropyl)-2,3-dihydrobenzofuran Molecular Formula: C11H15NO Molar mass: 177.24 g/mol [1] CAS Registry Number: 152623-93-3 Melting Point: Boiling Point: Flash Point: Solubility: Additionnal data: Notes:
The Dangers of 6-APDB
As with any psychoactive substance there is always an associated set of dangers which should be considered before its consumption. With 6-APDB these dangers are not clearly identified as the compound is still considered a novel research chemical with a very short history of use in humans and absolutely no formal trials conducted on its short term and long term effects and side effects. Likewise, 6-APDB acts as a central nervous system stimulants and may agitate known or unknown physical illnesses, specifically with the cardiovascular and respiratory system.
Additionally, 6-APDB has a profound effect over the psychological aspects of a human being, thus it should be avoided by users whom have a known mental illness, or are deemed not mentally fit for the consumption of psychoactive substances, as it may increase or instigate various symptoms and result in a psychotic meltdown or other similar occurrence.