Clonidine is a drug that acts as an alpha-2 adrenergic agonist, the main effect being lowering blood pressure because it decreases the release of norepinephine and epinephrine (adrenalin). It is prescribed for people with high blood pressure, as well as being the main pharmacological remedy for opioid withdrawal due to its effects on the central nervous system. It helps alleviate some of the physical withdrawal symptoms such as excessive sweating and hot/cold flashes.
Using Clonidine
Clonidine can be taken orally as prescribed for high blood pressure. Its use has also been reported in shaving soaps.Ways of Administration
Taking Clonidine Orally
Snorting Clonidine
Injecting Clonidine
Plugging Clonidine
Effects of Clonidine
Clonidine lowers blood pressure and eases symptoms of opioid withdrawal such as hot/cold flashes and excessive sweating. Clonidine can make the user drowsy or sleepy, and these effects are more prominent if clonidine is injected. Clonidine can have some anxiolytic (anxiety reducing) effects as well by relaxing the body.Combinations with Clonidine
Different Uses for Clonidine
Chemistry of Clonidine
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Column 1 Column 2 Systematic (IUPAC) name: N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine Synonyms: 2-(2,6-dichloroanilino)-2-imidazoline, 2,6-dichloro-N-2-imidazolidinylidenebenzenamine, 2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2), 2-[(2,6-dichlorophenyl)-imino]-2-imidazoline; ST-155, Catapres, Catapressan, Clonistada, Dixarit, Duraclon, Isoglaucon, Paracefan (hydrochloride) Molecular Formula: C9H9Cl2N3, C9H9Cl2N3.HCl Molar mass: 230.09 g/mol, 266.55 g/mol (hydrochloride) CAS Registry Number: 4205-90-7, 4205-91-8 (hydrochloride) Melting Point: 130°C, 305°C (hydrochloride) Boiling Point: no data Flash Point: no data Solubility: Freebase freely soluble in methanol, alcohol; Hydrochloride 1 g dissolves in 6 mL water (60°C), about 13 mL water (20°C), about 5.8 mL methanol, about 25 mL ethanol, about 5000 mL chloroform; soluble in absolute ethanol; slightly soluble in chloroform; practically insoluble in ether Additionnal data: none Notes: Freebase aspect : white to almost white crystals